ID   ST7_CHICK               Reviewed;         554 AA.
AC   A0M8U1;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Suppressor of tumorigenicity 7 protein homolog;
GN   Name=ST7;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12917688; DOI=10.1038/nature01858;
RA   Thomas J.W., Touchman J.W., Blakesley R.W., Bouffard G.G.,
RA   Beckstrom-Sternberg S.M., Margulies E.H., Blanchette M., Siepel A.C.,
RA   Thomas P.J., McDowell J.C., Maskeri B., Hansen N.F., Schwartz M.S.,
RA   Weber R.J., Kent W.J., Karolchik D., Bruen T.C., Bevan R., Cutler D.J.,
RA   Schwartz S., Elnitski L., Idol J.R., Prasad A.B., Lee-Lin S.-Q.,
RA   Maduro V.V.B., Summers T.J., Portnoy M.E., Dietrich N.L., Akhter N.,
RA   Ayele K., Benjamin B., Cariaga K., Brinkley C.P., Brooks S.Y., Granite S.,
RA   Guan X., Gupta J., Haghighi P., Ho S.-L., Huang M.C., Karlins E.,
RA   Laric P.L., Legaspi R., Lim M.J., Maduro Q.L., Masiello C.A.,
RA   Mastrian S.D., McCloskey J.C., Pearson R., Stantripop S., Tiongson E.E.,
RA   Tran J.T., Tsurgeon C., Vogt J.L., Walker M.A., Wetherby K.D.,
RA   Wiggins L.S., Young A.C., Zhang L.-H., Osoegawa K., Zhu B., Zhao B.,
RA   Shu C.L., De Jong P.J., Lawrence C.E., Smit A.F., Chakravarti A.,
RA   Haussler D., Green P., Miller W., Green E.D.;
RT   "Comparative analyses of multi-species sequences from targeted genomic
RT   regions.";
RL   Nature 424:788-793(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ST7 family. {ECO:0000305}.
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DR   EMBL; DP000235; AAR16244.2; -; Genomic_DNA.
DR   RefSeq; NP_001099142.1; NM_001105672.1.
DR   AlphaFoldDB; A0M8U1; -.
DR   SMR; A0M8U1; -.
DR   STRING; 9031.ENSGALP00000015265; -.
DR   PaxDb; A0M8U1; -.
DR   Ensembl; ENSGALT00000055784; ENSGALP00000045489; ENSGALG00000037206.
DR   GeneID; 417770; -.
DR   KEGG; gga:417770; -.
DR   CTD; 7982; -.
DR   VEuPathDB; HostDB:geneid_417770; -.
DR   eggNOG; KOG3807; Eukaryota.
DR   GeneTree; ENSGT00390000000873; -.
DR   HOGENOM; CLU_035578_2_0_1; -.
DR   InParanoid; A0M8U1; -.
DR   OMA; LLPSWHE; -.
DR   OrthoDB; 540550at2759; -.
DR   PhylomeDB; A0M8U1; -.
DR   PRO; PR:A0M8U1; -.
DR   Proteomes; UP000000539; Chromosome 1.
DR   Bgee; ENSGALG00000037206; Expressed in skeletal muscle tissue and 12 other tissues.
DR   ExpressionAtlas; A0M8U1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd11557; ST7; 1.
DR   InterPro; IPR007311; ST7.
DR   PANTHER; PTHR12745; PTHR12745; 1.
DR   Pfam; PF04184; ST7; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..554
FT                   /note="Suppressor of tumorigenicity 7 protein homolog"
FT                   /id="PRO_0000339219"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        489..509
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        516..536
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   554 AA;  63415 MW;  2FF4961A427A295D CRC64;
     MAEAGTGFLE QLKSCIVWSW TYLWTLWFFI MLFLVYILRV PLKINDNLTT VSMFLNTLTP
     KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH LRPLLGGVDN SAPSAANAAN
     GEADSSRQSV SECKVWRNPL NLFRGAEYNR YTWVTGREPL TYYDMNLSAQ DHQTFFTCDT
     DHLRPADAIM QKAWRERNPQ ARISAAHEAL ELNECATAYI LLAEEEATTI VEAEKLFKQA
     LKAGEGCYRR SQQLQHHGAQ YEAQHRRDTN VLVYIKRRLA MCARKLGRTR EAVKMMRDLM
     KEFPLLSMFN IHENLLEALL ELQAYADVQA VLAKYDDISL PKSATICYTA ALLKARAVSD
     KFSPEAASRR GLSTAEMNAV EAIHRAVEFN PHVPKYLLEM KSLILPPEHI LKRGDSEAIA
     YAFFHLQHWK RVEGALNLLH CTWEGTFRMI PYPLEKGHLF YPYPICTETA DRELLPSFHE
     VSVYPKKELP FFILFTAGLC SFTAMLALLT HQFPELMGVF AKAFLSTLFA PLNFVMEKVE
     SILPSSLWHQ LTRI