ID   ST7_DROPS               Reviewed;         541 AA.
AC   Q2M146;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 2.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Protein ST7 homolog;
GN   ORFNames=GA17575;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ST7 family. {ECO:0000305}.
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DR   EMBL; CH379069; EAL30730.2; -; Genomic_DNA.
DR   RefSeq; XP_001353227.2; XM_001353191.4.
DR   AlphaFoldDB; Q2M146; -.
DR   STRING; 7237.FBpp0274882; -.
DR   EnsemblMetazoa; FBtr0276444; FBpp0274882; FBgn0077586.
DR   GeneID; 4813442; -.
DR   KEGG; dpo:Dpse_GA17575; -.
DR   eggNOG; KOG3807; Eukaryota.
DR   HOGENOM; CLU_035578_2_0_1; -.
DR   InParanoid; Q2M146; -.
DR   OMA; YPESMGI; -.
DR   Proteomes; UP000001819; Chromosome X.
DR   Bgee; FBgn0077586; Expressed in female reproductive system and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd11557; ST7; 1.
DR   InterPro; IPR007311; ST7.
DR   PANTHER; PTHR12745; PTHR12745; 1.
DR   Pfam; PF04184; ST7; 2.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..541
FT                   /note="Protein ST7 homolog"
FT                   /id="PRO_0000339224"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          62..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  60475 MW;  1AEE4967D937590D CRC64;
     MWDSSMFLST LTPKFYVALT GTSSLISGLI LIFEWWYFRK YGTSFIEQVS INHISPWING
     NDAQSDSSNG SGSSTSSGSS SSSNGGGGGG GGGAGGGGPG AGGGTNSTTT TGTQMPECKV
     WRNPLNLFRG AEYQRFFWAT SKEPLTYYDM NLSAQDHQTF FTCEGDARKE EYEIMQTAWR
     ERNPMQRIKS AHNALEINAE CAPAYILLAE EEAMTIMEAE KILKTALKVA EINYRKSQAT
     QHQGAIADGM HRRDTNVLIY IKRRLAMCAR KLGKLKEAAK MFRDLTKEIP SIMSVLNIHE
     NLIETLLEMQ AYADCHAILA KYDDISLPKS ATICYTAALL KARAVADKFS PDIASKRGLS
     PAEMSAVEAI HRAVEFNPHV PKYLLETKPL ILPPEHILKR GDSEALAYAF FHLKHWKQVE
     GALNLLHCTW EGTFRMLPYP LERGHLFYPY PTCTECADRE LLPAFHEVSV YPKKELPFFI
     LFTAGLCSFT ALLALLTHQY PEPMGLLAQT VLTWISYPFQ LLKERVEAFW PCNLLQQLSR
     V