ID   ST7_HORSE               Reviewed;         585 AA.
AC   Q2QLA6;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Suppressor of tumorigenicity 7 protein;
GN   Name=ST7;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Antonellis A., Ayele K., Benjamin B., Blakesley R.W., Boakye A.,
RA   Bouffard G.G., Brinkley C., Brooks S., Chu G., Coleman H., Engle J.,
RA   Gestole M., Greene A., Guan X., Gupta J., Haghighi P., Han J., Hansen N.,
RA   Ho S.-L., Hu P., Hunter G., Hurle B., Idol J.R., Kwong P., Laric P.,
RA   Larson S., Lee-Lin S.-Q., Legaspi R., Madden M., Maduro Q.L., Maduro V.B.,
RA   Margulies E.H., Masiello C., Maskeri B., McDowell J., Mojidi H.A.,
RA   Mullikin J.C., Oestreicher J.S., Park M., Portnoy M.E., Prasad A., Puri O.,
RA   Reddix-Dugue N., Schandler K., Schueler M.G., Sison C., Stantripop S.,
RA   Stephen E., Taye A., Thomas J.W., Thomas P.J., Tsipouri V., Ung L.,
RA   Vogt J.L., Wetherby K.D., Young A., Green E.D.;
RT   "NISC comparative sequencing initiative.";
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ST7 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DP000020; ABB89803.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2QLA6; -.
DR   STRING; 9796.ENSECAP00000045094; -.
DR   PaxDb; Q2QLA6; -.
DR   Ensembl; ENSECAT00000058633; ENSECAP00000045094; ENSECAG00000008375.
DR   VGNC; VGNC:56054; ST7.
DR   GeneTree; ENSGT00390000000873; -.
DR   InParanoid; Q2QLA6; -.
DR   Proteomes; UP000002281; Chromosome 4.
DR   Bgee; ENSECAG00000008375; Expressed in cerebellum and 23 other tissues.
DR   ExpressionAtlas; Q2QLA6; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd11557; ST7; 1.
DR   InterPro; IPR007311; ST7.
DR   PANTHER; PTHR12745; PTHR12745; 1.
DR   Pfam; PF04184; ST7; 2.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..585
FT                   /note="Suppressor of tumorigenicity 7 protein"
FT                   /id="PRO_0000339201"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        512..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         386
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRC1"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   585 AA;  67152 MW;  7C11A89057EEADE7 CRC64;
     MAEAGTGFLE QLKSCIVWSW TYLWTVWFFI VLFLVYILRV PLKINDNLST VSMFLNTLTP
     KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH LRPLLGGVDN NSSNNSNSSN
     GDSDSNRQSV SECKVWRNPL NLFRGAEYNR YTWVTGREPL TYYDMNLSAQ DHQTFFTCDS
     DHLRPADAIM QKAWRERNPQ ARISAAHEAL EINEIRSRVE VPLIASSTIW EIKLLPKCAT
     AYILLAEEEA TTIAEAEKLF KQALKAGDGC YRRSQQLQHH GSQYEAQHRR DTNVLVYIKR
     RLAMCARRLG RTREAVKMMR DLMKEFPLLS MFNIHENLLE ALLELQAYAD VQAVLAKYDD
     ISLPKSATIC YTAALLKARA VSDKFSPEAA SRRGLSTAEM NAVEAIHRAV EFNPHVPKYL
     LEMKSLILPP EHILKRGDSE AIAYAFFHLA HWKRVEGALN LLHCTWEGTF RMIPYPLEKG
     HLFYPYPICT ETADRELLPS FHEVSVYPKK ELPFFILFTA GLCSFTAMLA LLTHQFPELM
     GVFAKAMIDI FCSAEFRDWN CKSIFMRVED ELEIPPAPQS QHFQN