ID   ST7_PIG                 Reviewed;         585 AA.
AC   Q2QLD7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Suppressor of tumorigenicity 7 protein;
GN   Name=ST7;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12917688; DOI=10.1038/nature01858;
RA   Thomas J.W., Touchman J.W., Blakesley R.W., Bouffard G.G.,
RA   Beckstrom-Sternberg S.M., Margulies E.H., Blanchette M., Siepel A.C.,
RA   Thomas P.J., McDowell J.C., Maskeri B., Hansen N.F., Schwartz M.S.,
RA   Weber R.J., Kent W.J., Karolchik D., Bruen T.C., Bevan R., Cutler D.J.,
RA   Schwartz S., Elnitski L., Idol J.R., Prasad A.B., Lee-Lin S.-Q.,
RA   Maduro V.V.B., Summers T.J., Portnoy M.E., Dietrich N.L., Akhter N.,
RA   Ayele K., Benjamin B., Cariaga K., Brinkley C.P., Brooks S.Y., Granite S.,
RA   Guan X., Gupta J., Haghighi P., Ho S.-L., Huang M.C., Karlins E.,
RA   Laric P.L., Legaspi R., Lim M.J., Maduro Q.L., Masiello C.A.,
RA   Mastrian S.D., McCloskey J.C., Pearson R., Stantripop S., Tiongson E.E.,
RA   Tran J.T., Tsurgeon C., Vogt J.L., Walker M.A., Wetherby K.D.,
RA   Wiggins L.S., Young A.C., Zhang L.-H., Osoegawa K., Zhu B., Zhao B.,
RA   Shu C.L., De Jong P.J., Lawrence C.E., Smit A.F., Chakravarti A.,
RA   Haussler D., Green P., Miller W., Green E.D.;
RT   "Comparative analyses of multi-species sequences from targeted genomic
RT   regions.";
RL   Nature 424:788-793(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ST7 family. {ECO:0000305}.
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DR   EMBL; DP000017; AAR16303.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q2QLD7; -.
DR   STRING; 9823.ENSSSCP00000017615; -.
DR   PRIDE; Q2QLD7; -.
DR   Ensembl; ENSSSCT00000057393; ENSSSCP00000053765; ENSSSCG00000016629.
DR   Ensembl; ENSSSCT00025094101; ENSSSCP00025041303; ENSSSCG00025067439.
DR   Ensembl; ENSSSCT00030096207; ENSSSCP00030044352; ENSSSCG00030068747.
DR   Ensembl; ENSSSCT00035029683; ENSSSCP00035011482; ENSSSCG00035022721.
DR   Ensembl; ENSSSCT00040053685; ENSSSCP00040022360; ENSSSCG00040040022.
DR   Ensembl; ENSSSCT00045033875; ENSSSCP00045023481; ENSSSCG00045019838.
DR   Ensembl; ENSSSCT00050055259; ENSSSCP00050023402; ENSSSCG00050040769.
DR   Ensembl; ENSSSCT00055040253; ENSSSCP00055032025; ENSSSCG00055020512.
DR   Ensembl; ENSSSCT00060094092; ENSSSCP00060040711; ENSSSCG00060068810.
DR   Ensembl; ENSSSCT00065099078; ENSSSCP00065043474; ENSSSCG00065071978.
DR   Ensembl; ENSSSCT00070057534; ENSSSCP00070048918; ENSSSCG00070028628.
DR   eggNOG; KOG3807; Eukaryota.
DR   GeneTree; ENSGT00390000000873; -.
DR   InParanoid; Q2QLD7; -.
DR   Proteomes; UP000008227; Chromosome 18.
DR   Proteomes; UP000314985; Chromosome 18.
DR   Bgee; ENSSSCG00000016629; Expressed in cerebellum and 43 other tissues.
DR   ExpressionAtlas; Q2QLD7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd11557; ST7; 1.
DR   InterPro; IPR007311; ST7.
DR   PANTHER; PTHR12745; PTHR12745; 1.
DR   Pfam; PF04184; ST7; 2.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..585
FT                   /note="Suppressor of tumorigenicity 7 protein"
FT                   /id="PRO_0000339212"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        512..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         386
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRC1"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   585 AA;  67152 MW;  7C11A89057EEADE7 CRC64;
     MAEAGTGFLE QLKSCIVWSW TYLWTVWFFI VLFLVYILRV PLKINDNLST VSMFLNTLTP
     KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH LRPLLGGVDN NSSNNSNSSN
     GDSDSNRQSV SECKVWRNPL NLFRGAEYNR YTWVTGREPL TYYDMNLSAQ DHQTFFTCDS
     DHLRPADAIM QKAWRERNPQ ARISAAHEAL EINEIRSRVE VPLIASSTIW EIKLLPKCAT
     AYILLAEEEA TTIAEAEKLF KQALKAGDGC YRRSQQLQHH GSQYEAQHRR DTNVLVYIKR
     RLAMCARRLG RTREAVKMMR DLMKEFPLLS MFNIHENLLE ALLELQAYAD VQAVLAKYDD
     ISLPKSATIC YTAALLKARA VSDKFSPEAA SRRGLSTAEM NAVEAIHRAV EFNPHVPKYL
     LEMKSLILPP EHILKRGDSE AIAYAFFHLA HWKRVEGALN LLHCTWEGTF RMIPYPLEKG
     HLFYPYPICT ETADRELLPS FHEVSVYPKK ELPFFILFTA GLCSFTAMLA LLTHQFPELM
     GVFAKAMIDI FCSAEFRDWN CKSIFMRVED ELEIPPAPQS QHFQN