ID   ST7_PONAB               Reviewed;         585 AA.
AC   Q2IBE0;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Suppressor of tumorigenicity 7 protein;
GN   Name=ST7;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Antonellis A., Ayele K., Benjamin B., Blakesley R.W., Boakye A.,
RA   Bouffard G.G., Brinkley C., Brooks S., Chu G., Coleman H., Engle J.,
RA   Gestole M., Greene A., Guan X., Gupta J., Haghighi P., Han J., Hansen N.,
RA   Ho S.-L., Hu P., Hunter G., Hurle B., Idol J.R., Kwong P., Laric P.,
RA   Larson S., Lee-Lin S.-Q., Legaspi R., Madden M., Maduro Q.L., Maduro V.B.,
RA   Margulies E.H., Masiello C., Maskeri B., McDowell J., Mojidi H.A.,
RA   Mullikin J.C., Oestreicher J.S., Park M., Portnoy M.E., Prasad A., Puri O.,
RA   Reddix-Dugue N., Schandler K., Schueler M.G., Sison C., Stantripop S.,
RA   Stephen E., Taye A., Thomas J.W., Thomas P.J., Tsipouri V., Ung L.,
RA   Vogt J.L., Wetherby K.D., Young A., Green E.D.;
RT   "NISC comparative sequencing initiative.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ST7 family. {ECO:0000305}.
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DR   EMBL; DP000026; ABC87463.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2IBE0; -.
DR   STRING; 9601.ENSPPYP00000020108; -.
DR   Ensembl; ENSPPYT00000054234; ENSPPYP00000039707; ENSPPYG00000017934.
DR   eggNOG; KOG3807; Eukaryota.
DR   GeneTree; ENSGT00390000000873; -.
DR   InParanoid; Q2IBE0; -.
DR   OrthoDB; 540550at2759; -.
DR   Proteomes; UP000001595; Chromosome 7.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd11557; ST7; 1.
DR   InterPro; IPR007311; ST7.
DR   PANTHER; PTHR12745; PTHR12745; 1.
DR   Pfam; PF04184; ST7; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..585
FT                   /note="Suppressor of tumorigenicity 7 protein"
FT                   /id="PRO_0000339213"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        512..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         386
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRC1"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   585 AA;  67188 MW;  7BA897429687307F CRC64;
     MAEAATGFLE QLKSCIVWSW TYLWTVWFFI VLFLVYILRV PLKINDNLST VSMFLNTLTP
     KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH LRPLLGGVDN NSSNNSNSSN
     GDSDSNRQSV SECKVWRNPL NLFRGAEYNR YTWVTGREPL TYYDMNLSAQ DHQTFFTCDS
     DHLRPADAIM QKAWRERNPQ ARISAAHEAL EINEIRSRVE VPLIASSTIW EIKLLPKCAT
     AYILLAEEEA TTIAEAEKLF KQALKAGDGC YRRSQQLQHH GSQYEAQHRR DTNVLVYIKR
     RLAMCARRLG RTREAVKMMR DLMKEFPLLS MFNIHENLLE ALLELQAYAD VQAVLAKYDD
     ISLPKSATIC YTAALLKARA VSDKFSPEAA SRRGLSTAEM NAVEAIHRAV EFNPHVPKYL
     LEMKSLILPP EHILKRGDSE AIAYAFFHLA HWKRVEGALN LLHCTWEGTF RMIPYPLEKG
     HLFYPYPICT ETADRELLPS FHEVSVYPKK ELPFFILFTA GLCSFTAMLA LLTHQFPELM
     GVFAKAMIDI FCSAEFRHWN CKSIFMRVED ELEIPPAPQS QHFQN