ID   STAA_DICDI              Reviewed;         157 AA.
AC   P08797; Q54VK9;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Stalk-specific protein A;
DE   AltName: Full=DIF-inducible protein;
DE   Flags: Precursor;
GN   Name=staA; ORFNames=DDB_G0294473;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, AND INDUCTION.
RX   PubMed=3380704; DOI=10.1093/nar/16.10.4738;
RA   McRobbie S.J., Ceccarelli A.;
RT   "Complete nucleotide sequence of a DIF-inducible, stalk-specific mRNA from
RT   Dictyostelium discoideum.";
RL   Nucleic Acids Res. 16:4738-4738(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Selectively expressed in stalk cells.
CC       {ECO:0000269|PubMed:3380704}.
CC   -!- INDUCTION: By the stalk-specific morphogen DIF (Differentiation
CC       inducing factor). {ECO:0000269|PubMed:3380704}.
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DR   EMBL; X07859; CAA30707.1; -; mRNA.
DR   EMBL; AAFI02000035; EAL67364.1; -; Genomic_DNA.
DR   PIR; A28299; A28299.
DR   RefSeq; XP_641346.1; XM_636254.1.
DR   AlphaFoldDB; P08797; -.
DR   STRING; 44689.DDB0231127; -.
DR   PaxDb; P08797; -.
DR   EnsemblProtists; EAL67364; EAL67364; DDB_G0294473.
DR   GeneID; 8622480; -.
DR   KEGG; ddi:DDB_G0294473; -.
DR   dictyBase; DDB_G0294473; staA.
DR   eggNOG; ENOG502RHTW; Eukaryota.
DR   HOGENOM; CLU_117893_0_0_1; -.
DR   InParanoid; P08797; -.
DR   OMA; DAVCSCI; -.
DR   PhylomeDB; P08797; -.
DR   PRO; PR:P08797; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IBA:GO_Central.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; IBA:GO_Central.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.290; -; 1.
DR   InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR   InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR   InterPro; IPR019028; CBM_49.
DR   Pfam; PF09478; CBM49; 1.
DR   SMART; SM01063; CBM49; 1.
DR   SUPFAM; SSF49384; SSF49384; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Reference proteome; Secreted;
KW   Signal; Sporulation.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..157
FT                   /note="Stalk-specific protein A"
FT                   /id="PRO_0000021106"
FT   CONFLICT        95
FT                   /note="A -> D (in Ref. 1; CAA30707)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        101
FT                   /note="R -> K (in Ref. 1; CAA30707)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   157 AA;  17412 MW;  F74B07394355779B CRC64;
     MRSILILLSL LLTIAFASAS FPYQCGPYSC QFGQVCRIDN GVCNCIPIND CHEVSLSTKV
     VGTWVDGSRG NKRFTQYDIT ITNNLNTNIK QIYIATDYTL RLRDHSNTSI WNVNLLPNGI
     LTLPSYQPSI NAHASFTFGF ILEGTQPANL NVLSVSF