STAB_DICDI
ID STAB_DICDI Reviewed; 157 AA.
AC Q54VL1; O96941;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Stalk-specific protein B;
DE Flags: Precursor;
GN Name=staB; ORFNames=DDB_G0294499;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC STRAIN=AX2;
RX PubMed=9203345; DOI=10.1046/j.1432-0436.1997.6140223.x;
RA Robinson V., Williams J.;
RT "A marker of terminal stalk cell terminal differentiation in
RT Dictyostelium.";
RL Differentiation 61:223-228(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Selectively expressed in stalk cells. If an
CC aggregate enters culmination immediately it is expressed in the bottom
CC half of the stalk and in the basal disk but if a migratory slug is
CC formed it is also expressed in the top of the stalk and in a disk of
CC cells that surmounts the spore head. {ECO:0000269|PubMed:9203345}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA73552.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; Y13098; CAA73552.1; ALT_FRAME; mRNA.
DR EMBL; AAFI02000035; EAL67363.1; -; Genomic_DNA.
DR RefSeq; XP_641344.1; XM_636252.1.
DR AlphaFoldDB; Q54VL1; -.
DR STRING; 44689.DDB0233051; -.
DR PaxDb; Q54VL1; -.
DR EnsemblProtists; EAL67363; EAL67363; DDB_G0294499.
DR GeneID; 8622478; -.
DR KEGG; ddi:DDB_G0294499; -.
DR dictyBase; DDB_G0294499; staB.
DR eggNOG; ENOG502RHTW; Eukaryota.
DR HOGENOM; CLU_117893_0_0_1; -.
DR InParanoid; Q54VL1; -.
DR OMA; SNCIPIN; -.
DR PhylomeDB; Q54VL1; -.
DR PRO; PR:Q54VL1; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005201; F:extracellular matrix structural constituent; IBA:GO_Central.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IBA:GO_Central.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.290; -; 1.
DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR InterPro; IPR019028; CBM_49.
DR Pfam; PF09478; CBM49; 1.
DR SMART; SM01063; CBM49; 1.
DR SUPFAM; SSF49384; SSF49384; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Reference proteome; Secreted;
KW Signal; Sporulation.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..157
FT /note="Stalk-specific protein B"
FT /id="PRO_0000311886"
FT CONFLICT 43
FT /note="S -> SP (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
FT CONFLICT 47
FT /note="P -> Q (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
FT CONFLICT 89
FT /note="I -> II (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
FT CONFLICT 118
FT /note="N -> NV (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
FT CONFLICT 133
FT /note="H -> HMV (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
FT CONFLICT 140
FT /note="L -> F (in Ref. 1; CAA73552)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 157 AA; 17375 MW; C1E7B0F3E458C144 CRC64;
MRSILILLSL LLTIAFASAS FPYQCGPYSC QFGQVCRIDN GVSNCIPIND CHEVSLSTKV
VGTWVDGSRG NKRFTQYDIT ITNNLNTNIK QIYIATDYTL RLRDHSNNSI WNVNLLPNGI
LTLPSYQPSI NAHASFTFGL IIEGTQPANL NVLSVSF
