STAD6_ORYSJ
ID STAD6_ORYSJ Reviewed; 419 AA.
AC Q0J7E4; A0A0P0XD46; Q6Z1J5;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Acyl-[acyl-carrier-protein] desaturase 6, chloroplastic;
DE EC=1.14.19.-;
DE Flags: Precursor;
GN OrderedLocusNames=Os08g0199400, LOC_Os08g09950; ORFNames=OSJNBb0094P23.29;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=19522564; DOI=10.1094/mpmi-22-7-0820;
RA Jiang C.J., Shimono M., Maeda S., Inoue H., Mori M., Hasegawa M.,
RA Sugano S., Takatsuji H.;
RT "Suppression of the rice fatty-acid desaturase gene OsSSI2 enhances
RT resistance to blast and leaf blight diseases in rice.";
RL Mol. Plant Microbe Interact. 22:820-829(2009).
CC -!- FUNCTION: Introduces a cis double bond in the acyl chain of an acyl-
CC [acyl-carrier protein]. {ECO:0000305}.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000250|UniProtKB:P22337};
CC Note=Binds 2 Fe(2+) ions per subunit. {ECO:0000250|UniProtKB:P22337};
CC -!- PATHWAY: Lipid metabolism; fatty acid metabolism.
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P22337}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 2 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD03577.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AP005416; BAD03577.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP008214; BAF23121.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT04247.1; -; Genomic_DNA.
DR EMBL; AK105852; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015650772.1; XM_015795286.1.
DR AlphaFoldDB; Q0J7E4; -.
DR SMR; Q0J7E4; -.
DR STRING; 4530.OS08T0199400-01; -.
DR PaxDb; Q0J7E4; -.
DR PRIDE; Q0J7E4; -.
DR EnsemblPlants; Os08t0199400-01; Os08t0199400-01; Os08g0199400.
DR GeneID; 4344895; -.
DR Gramene; Os08t0199400-01; Os08t0199400-01; Os08g0199400.
DR KEGG; osa:4344895; -.
DR eggNOG; ENOG502QRJK; Eukaryota.
DR HOGENOM; CLU_034505_1_0_1; -.
DR InParanoid; Q0J7E4; -.
DR OMA; FDMREVE; -.
DR OrthoDB; 608188at2759; -.
DR UniPathway; UPA00199; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q0J7E4; OS.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0045300; F:acyl-[acyl-carrier-protein] desaturase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR CDD; cd01050; Acyl_ACP_Desat; 1.
DR Gene3D; 1.10.620.20; -; 1.
DR InterPro; IPR005067; Fatty_acid_desaturase-2.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR012348; RNR-like.
DR PANTHER; PTHR31155; PTHR31155; 1.
DR Pfam; PF03405; FA_desaturase_2; 1.
DR PIRSF; PIRSF000346; Dlt9_acylACP_des; 1.
DR SUPFAM; SSF47240; SSF47240; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Fatty acid biosynthesis; Fatty acid metabolism; Iron;
KW Lipid biosynthesis; Lipid metabolism; Metal-binding; Oxidoreductase;
KW Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..54
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 55..419
FT /note="Acyl-[acyl-carrier-protein] desaturase 6,
FT chloroplastic"
FT /id="PRO_0000401434"
FT BINDING 151
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 189
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 189
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 192
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 242
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 277
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 277
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT BINDING 280
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P22337"
FT CONFLICT 64
FT /note="R -> W (in Ref. 4; AK105852)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 419 AA; 46101 MW; 238A68652D1A18D9 CRC64;
MAATATMAMP LANRLRCKPN TNSSSPSRTL FGRRVTMISS SRWGSAVSGS AIMSAAADVA
AAVRREEDEE MRSYLSPEKL EVLTQMEPWV EEHVLPLLKP VEAAWQPSDL LPDPAVLGGE
GFHAACAELR ERAAGVPDLL LVCLVANMVT EEALPTYQSS LNRVRAVGDL TGADATAWAR
WIRGWSAEEN RHGDVLNRYM YLSGRFDMAE VERAVHRLIR SGMAVDPPCS PYHAFVYTAF
QERATAVAHG NTARLVGARG HGDAALARVC GTVAADEKRH EAAYTRIVSR LLEADPDAGV
RAVARMLRRG VAMPTSPISD GRRDDLYACV VSLAEQAGTY TVSDYCSIVE HLVREWRVEE
LAAGLSGEGR RARDYVCELP QKIRRMKEKA HERAVKAQKK PISIPINWIF DRHVSVMLP
