STAR2_ORYSJ
ID STAR2_ORYSJ Reviewed; 285 AA.
AC Q5W7C1; A0A0P0WHB4; Q9LIX5;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=UPF0014 membrane protein STAR2 {ECO:0000305};
DE AltName: Full=Protein SENSITIVE TO ALUMINUM RHIZOTOXICITY 2 {ECO:0000303|PubMed:19244140};
GN Name=STAR2 {ECO:0000303|PubMed:19244140};
GN OrderedLocusNames=Os05g0119000 {ECO:0000312|EMBL:BAF16393.1},
GN LOC_Os05g02750 {ECO:0000305};
GN ORFNames=P0496H07.22 {ECO:0000312|EMBL:AAV44213.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH STAR2, SUBCELLULAR
RP LOCATION, TISSUE SPECIFICITY, INDUCTION BY ALUMINUM, AND DISRUPTION
RP PHENOTYPE.
RC STRAIN=cv. Nipponbare;
RX PubMed=19244140; DOI=10.1105/tpc.108.064543;
RA Huang C.F., Yamaji N., Mitani N., Yano M., Nagamura Y., Ma J.F.;
RT "A bacterial-type ABC transporter is involved in aluminum tolerance in
RT rice.";
RL Plant Cell 21:655-667(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP INDUCTION BY ALUMINUM.
RX PubMed=19880795; DOI=10.1105/tpc.109.070771;
RA Yamaji N., Huang C.F., Nagao S., Yano M., Sato Y., Nagamura Y., Ma J.F.;
RT "A zinc finger transcription factor ART1 regulates multiple genes
RT implicated in aluminum tolerance in rice.";
RL Plant Cell 21:3339-3349(2009).
CC -!- FUNCTION: Associates with STAR2 to form a functional transmembrane ABC
CC transporter required for detoxification of aluminum (Al) in roots. Can
CC specifically transport UDP-glucose. {ECO:0000269|PubMed:19244140}.
CC -!- SUBUNIT: Interacts with STAR2. {ECO:0000269|PubMed:19244140}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:19244140}; Multi-
CC pass membrane protein {ECO:0000269|PubMed:19244140}.
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:19244140}.
CC -!- INDUCTION: By Al in roots. Positively regulated by ART1.
CC {ECO:0000269|PubMed:19244140, ECO:0000269|PubMed:19880795}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC condition, but strong inhibition of root elongation when grown in the
CC presence of Al. {ECO:0000269|PubMed:19244140}.
CC -!- SIMILARITY: Belongs to the UPF0014 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA90494.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB379845; BAH28260.1; -; mRNA.
DR EMBL; AC078977; AAV44213.1; -; Genomic_DNA.
DR EMBL; AP001111; BAA90494.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008211; BAF16393.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS91994.1; -; Genomic_DNA.
DR EMBL; AK069359; BAG91401.1; -; mRNA.
DR RefSeq; XP_015637768.1; XM_015782282.1.
DR AlphaFoldDB; Q5W7C1; -.
DR STRING; 4530.OS05T0119000-01; -.
DR TCDB; 3.A.1.139.1; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q5W7C1; -.
DR PRIDE; Q5W7C1; -.
DR EnsemblPlants; Os05t0119000-01; Os05t0119000-01; Os05g0119000.
DR GeneID; 4337635; -.
DR Gramene; Os05t0119000-01; Os05t0119000-01; Os05g0119000.
DR KEGG; osa:4337635; -.
DR eggNOG; ENOG502RHEJ; Eukaryota.
DR HOGENOM; CLU_076147_1_0_1; -.
DR InParanoid; Q5W7C1; -.
DR OMA; PWYEPQY; -.
DR OrthoDB; 1036153at2759; -.
DR PlantReactome; R-OSA-9639136; Response to Aluminum stress.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR ExpressionAtlas; Q5W7C1; baseline and differential.
DR Genevisible; Q5W7C1; OS.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0012506; C:vesicle membrane; IDA:UniProtKB.
DR GO; GO:0005460; F:UDP-glucose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0010044; P:response to aluminum ion; IMP:UniProtKB.
DR GO; GO:0015786; P:UDP-glucose transmembrane transport; IDA:UniProtKB.
DR InterPro; IPR005226; UPF0014_fam.
DR PANTHER; PTHR30028; PTHR30028; 1.
DR Pfam; PF03649; UPF0014; 1.
DR TIGRFAMs; TIGR00245; TIGR00245; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..285
FT /note="UPF0014 membrane protein STAR2"
FT /id="PRO_0000405577"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..225
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 285 AA; 30311 MW; EA820C2C5E40BC0C CRC64;
MMASMAALLQ RLLVVVNQVD PGAPGFWREF LVGMLKPVAA TAVVAMAVAL SFTQRLGLEG
EMLYAMARAF LQLSVIGFVL QFIFTQKSAA WILLAYLFMV TVAGYTAGQR ARHVPRGKHI
AAVSILAGTS VTMALLVALR VFPFTPRYII PVAGMMVGNA MTVTGVTMKK LREDVGMQRG
VVETALALGA TPRQATARQV RRSLVIALSP VIDNAKTVGL IALPGAMTGL IMGGASPLEA
IQLQIVVMNM LMGASTVSSI LSTYLCWPAF FTGAFQLNDA VFAAD
