STAR5_BOVIN
ID STAR5_BOVIN Reviewed; 213 AA.
AC A1A4M6;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=StAR-related lipid transfer protein 5;
DE AltName: Full=START domain-containing protein 5;
DE Short=StARD5;
GN Name=STARD5;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal skin;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the intracellular transport of sterols or
CC other lipids. May bind cholesterol or other sterols (By similarity).
CC {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC126727; AAI26728.1; -; mRNA.
DR RefSeq; NP_001073734.1; NM_001080265.1.
DR AlphaFoldDB; A1A4M6; -.
DR SMR; A1A4M6; -.
DR STRING; 9913.ENSBTAP00000014559; -.
DR PaxDb; A1A4M6; -.
DR PRIDE; A1A4M6; -.
DR Ensembl; ENSBTAT00000014559; ENSBTAP00000014559; ENSBTAG00000010964.
DR GeneID; 512369; -.
DR KEGG; bta:512369; -.
DR CTD; 80765; -.
DR VEuPathDB; HostDB:ENSBTAG00000010964; -.
DR VGNC; VGNC:35366; STARD5.
DR eggNOG; KOG3845; Eukaryota.
DR GeneTree; ENSGT00940000159159; -.
DR HOGENOM; CLU_093200_1_0_1; -.
DR InParanoid; A1A4M6; -.
DR OMA; GCPPQSG; -.
DR OrthoDB; 1469639at2759; -.
DR Reactome; R-BTA-159418; Recycling of bile acids and salts.
DR Proteomes; UP000009136; Chromosome 21.
DR Bgee; ENSBTAG00000010964; Expressed in zone of skin and 101 other tissues.
DR GO; GO:0032052; F:bile acid binding; IEA:InterPro.
DR GO; GO:0015485; F:cholesterol binding; IBA:GO_Central.
DR GO; GO:0120020; F:cholesterol transfer activity; IBA:GO_Central.
DR GO; GO:0070508; P:cholesterol import; IBA:GO_Central.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR029868; StARD5.
DR InterPro; IPR043556; StARD5/6.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR46374; PTHR46374; 1.
DR PANTHER; PTHR46374:SF3; PTHR46374:SF3; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00234; START; 1.
DR PROSITE; PS50848; START; 1.
PE 2: Evidence at transcript level;
KW Lipid transport; Lipid-binding; Reference proteome; Transport.
FT CHAIN 1..213
FT /note="StAR-related lipid transfer protein 5"
FT /id="PRO_0000280535"
FT DOMAIN 1..213
FT /note="START"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
SQ SEQUENCE 213 AA; 23573 MW; 3183BDC2E38D2946 CRC64;
MDLATAAQVS EAVAEKMLQY RRDKSGWKIC REGNGVSVSW RPSVEFPGNL YKGEGIVNGT
PEQVWDCVKP LAGTLRAQWD ENVNSFEIIE SLTDTLLFSR TTTPSAVMKL ISPRDFVDLI
LVRTYEDGTI SSNAANVEHP SCPPNPAYVR GFNHPCGCFC EPLPGEPNKT SLVTFFQTDL
SGYLPQSVVD SFFPRSMAGF YANLEKAVKK FFG