STAR5_PONAB
ID STAR5_PONAB Reviewed; 213 AA.
AC Q5R8P9;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=StAR-related lipid transfer protein 5;
DE AltName: Full=START domain-containing protein 5;
DE Short=StARD5;
GN Name=STARD5;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the intracellular transport of sterols or
CC other lipids. May bind cholesterol or other sterols (By similarity).
CC {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR859702; CAH91861.1; -; mRNA.
DR RefSeq; NP_001126078.1; NM_001132606.1.
DR RefSeq; XP_009248370.1; XM_009250095.1.
DR AlphaFoldDB; Q5R8P9; -.
DR BMRB; Q5R8P9; -.
DR SMR; Q5R8P9; -.
DR STRING; 9601.ENSPPYP00000007629; -.
DR GeneID; 100173030; -.
DR KEGG; pon:100173030; -.
DR CTD; 80765; -.
DR eggNOG; KOG3845; Eukaryota.
DR HOGENOM; CLU_093200_1_0_1; -.
DR InParanoid; Q5R8P9; -.
DR OMA; GCPPQSG; -.
DR OrthoDB; 1469639at2759; -.
DR Proteomes; UP000001595; Chromosome 15.
DR GO; GO:0032052; F:bile acid binding; IEA:InterPro.
DR GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR GO; GO:0120020; F:cholesterol transfer activity; IEA:Ensembl.
DR GO; GO:0070508; P:cholesterol import; IEA:Ensembl.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR029868; StARD5.
DR InterPro; IPR043556; StARD5/6.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR46374; PTHR46374; 1.
DR PANTHER; PTHR46374:SF3; PTHR46374:SF3; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00234; START; 1.
DR PROSITE; PS50848; START; 1.
PE 2: Evidence at transcript level;
KW Lipid transport; Lipid-binding; Reference proteome; Transport.
FT CHAIN 1..213
FT /note="StAR-related lipid transfer protein 5"
FT /id="PRO_0000220671"
FT DOMAIN 1..213
FT /note="START"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
SQ SEQUENCE 213 AA; 23826 MW; BE592A1D3ECC74D8 CRC64;
MDPALAAQMS EAVAEKMLQY RRDTAGWKIC REGNGVSVSW RPSMEFPGNL YRGEGIVYGT
LEEVWDCVKP AVGGLRVKWD ENVTGFEIIQ SITDTLCVSR TSTPSAAMKL ISPRDFVDLV
LVKRYEDGTI SSNATHVEHP LCPPKPGFVR GFNHPCGCFC EPLPGEPTKT NLVTFFHTDL
SGYLPQNVVD SFFPRSMTRF YANLQKAVKQ FHE