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STB2_YEAST
ID   STB2_YEAST              Reviewed;         850 AA.
AC   P46679; D6VZM8;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Protein STB2;
GN   Name=STB2; OrderedLocusNames=YMR053C; ORFNames=YM9796.06C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INTERACTION WITH SIN3.
RX   PubMed=9393435; DOI=10.1007/s004380050581;
RA   Kasten M.M., Stillman D.J.;
RT   "Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding
RT   Sin3p binding proteins.";
RL   Mol. Gen. Genet. 256:376-386(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169872;
RA   Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA   Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA   Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA   Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL   Nature 387:90-93(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 609-850.
RC   STRAIN=SC252;
RX   PubMed=7483842; DOI=10.1002/yea.320110710;
RA   Horecka J.;
RT   "Localization of the FAR3 gene: genetic mapping and molecular cloning using
RT   a chromosome walk-'n'-roll strategy.";
RL   Yeast 11:691-696(1995).
RN   [5]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-594, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA   Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT   "A multidimensional chromatography technology for in-depth phosphoproteome
RT   analysis.";
RL   Mol. Cell. Proteomics 7:1389-1396(2008).
RN   [6]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-625, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19779198; DOI=10.1126/science.1172867;
RA   Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT   "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT   into evolution.";
RL   Science 325:1682-1686(2009).
CC   -!- SUBUNIT: Interacts with SIN3. {ECO:0000269|PubMed:9393435}.
CC   -!- SIMILARITY: To yeast STB6. {ECO:0000305}.
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DR   EMBL; U33438; AAA75481.1; -; Genomic_DNA.
DR   EMBL; Z49703; CAA89763.1; -; Genomic_DNA.
DR   EMBL; U35609; AAB39036.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA09952.1; -; Genomic_DNA.
DR   PIR; S54553; S54553.
DR   RefSeq; NP_013769.1; NM_001182551.1.
DR   AlphaFoldDB; P46679; -.
DR   BioGRID; 35229; 116.
DR   DIP; DIP-1725N; -.
DR   IntAct; P46679; 4.
DR   MINT; P46679; -.
DR   STRING; 4932.YMR053C; -.
DR   iPTMnet; P46679; -.
DR   PaxDb; P46679; -.
DR   PRIDE; P46679; -.
DR   EnsemblFungi; YMR053C_mRNA; YMR053C; YMR053C.
DR   GeneID; 855075; -.
DR   KEGG; sce:YMR053C; -.
DR   SGD; S000004657; STB2.
DR   VEuPathDB; FungiDB:YMR053C; -.
DR   eggNOG; ENOG502QT8Q; Eukaryota.
DR   GeneTree; ENSGT00940000176579; -.
DR   HOGENOM; CLU_010065_0_0_1; -.
DR   InParanoid; P46679; -.
DR   OMA; YIVEQWI; -.
DR   BioCyc; YEAST:G3O-32758-MON; -.
DR   PRO; PR:P46679; -.
DR   Proteomes; UP000002311; Chromosome XIII.
DR   RNAct; P46679; protein.
DR   GO; GO:0070822; C:Sin3-type complex; IDA:SGD.
DR   InterPro; IPR038919; Stb2/Stb6.
DR   PANTHER; PTHR31011; PTHR31011; 2.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..850
FT                   /note="Protein STB2"
FT                   /id="PRO_0000072252"
FT   MOD_RES         594
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:18407956"
FT   MOD_RES         625
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19779198"
SQ   SEQUENCE   850 AA;  97828 MW;  DEB5AF3F442592E9 CRC64;
     MVMADTIATG DKTSQFDGKH MQDLERIYST RDTLDDNFFG ERGQKDANGD YYDELNNEET
     NYSGSSYYGH SDDSEVVGLI KNDTVSQLPP LDSFIFPDSR ALFLLDLGNY ADLTYEEIIV
     HGFEIYIVEQ WVACRNLSTL ITSYTGNSQD TISGVRVVLP KDTSMWPGRF RLYFEELMEF
     ARPKFTPKGT LFITNLSGVS FGLNLLHVEC GDLRTIWKDF EVNFDLKNLH CGGRSANLLC
     PPTMASLDKF SQLFKIPTNG FIAQYPQMIQ QQQPRLPEEE YKTVGNSKCR NTDSKSPVVE
     MVTLIQISLS YFNLLSKNYQ TDGLLCEDTK RAIDEWWETY GKLYLGTEKP RNECTLGPTT
     VAGLISLILC CYFKLMIENC ISSKDPFDEA GFFQGIYNFQ KKHGLNKRKS RVYLDPRTLE
     KLFEVTAKVS SKDIFKLKKM VTSTVQDIIG KGNPINLSHK ILTTDLDTLI HNIHGGSVGL
     LWKGKGHPRK CCTDISNEEF LKFNYQRGDP DGQIREREML LEKFRLERIA YAQKHASKKV
     SSSSLDTSED IGRTNAMPSS ATVSSMFPNY DNTKYAYNFG INKLYQGEYY RRNSFPYCKD
     RTHDNIYEDL SELKEKSSRL YRCNSSSAVQ NIVEKWDLPF DPSVVRIARD LLRMKYDIQA
     QQHIQEMDEH YMGKLNKEGT VGQYSKFNER YKRLQELYKK YSDGAKVFEG RFEDIDNKQQ
     LLLHEMQELN SLSSRLKYDM RILEVRVRDI ESSVAQFDSK LIGLKSSLQG QGKTGICSAI
     DPKSDKDEYD RCVNDLMTTN NPTYEALCLK MLSRRYFKDL KNDTVGWFRW LFGNNSLHNN
     ASEDDRGIRV
 
 
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