ID   STC2_CAVPO              Reviewed;         197 AA.
AC   P57675;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Stanniocalcin-2;
DE            Short=STC-2;
DE   Flags: Fragments;
GN   Name=STC2;
OS   Cavia porcellus (Guinea pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC   Cavia.
OX   NCBI_TaxID=10141;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=10450831; DOI=10.1055/s-2007-978764;
RA   Moore E.E., Kuestner R.E., Conklin D.C., Whitmore T.E., Downey W.,
RA   Buddle M.M., Adams R.L., Bell L.A., Thompson D.L., Wolf A., Chen L.,
RA   Stamm M.R., Grant F.J., Lok S., Ren H., de Jongh K.S.;
RT   "Stanniocalcin 2: characterization of the protein and its localization to
RT   human pancreatic alpha cells.";
RL   Horm. Metab. Res. 31:406-414(1999).
CC   -!- FUNCTION: Has an anti-hypocalcemic action on calcium and phosphate
CC       homeostasis.
CC   -!- SUBUNIT: Homodimer; disulfide-linked. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the stanniocalcin family. {ECO:0000305}.
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DR   InParanoid; P57675; -.
DR   Proteomes; UP000005447; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR004978; Stanniocalcin.
DR   PANTHER; PTHR11245; PTHR11245; 1.
DR   Pfam; PF03298; Stanniocalcin; 2.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Hormone; Reference proteome;
KW   Secreted.
FT   CHAIN           1..197
FT                   /note="Stanniocalcin-2"
FT                   /id="PRO_0000182019"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..181
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_CONS        60..61
FT                   /evidence="ECO:0000305"
FT   NON_CONS        64..65
FT                   /evidence="ECO:0000305"
FT   NON_CONS        69..70
FT                   /evidence="ECO:0000305"
FT   NON_CONS        75..76
FT                   /evidence="ECO:0000305"
FT   NON_CONS        92..93
FT                   /evidence="ECO:0000305"
FT   NON_CONS        154..155
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   197 AA;  21911 MW;  1512DA859C8A8E67 CRC64;
     TDAXNPPEGP QDRGSQQKGR LSLQNTAEIQ HCLVNAGDVG CGVFECFENN XCXIXXLHXI
     SFIKAHALRF GCISREMVFQ LQRECYLKHD LCMINFRDLL LHEPYVDLVN LLLTCGEDVK
     EAVTRSIQAQ CEQNWGGLCS ILSFCTSNVQ RPXAXQPXAD RAQVSRPHHH DTGHHLLEAI
     XGAKGERGSK SHPSVRA