ID   STE11_PNECA             Reviewed;         501 AA.
AC   Q870J1;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=HMG-box protein STE11;
OS   Pneumocystis carinii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Pneumocystidomycetes; Pneumocystidaceae; Pneumocystis.
OX   NCBI_TaxID=4754;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAP13349.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PHOSPHORYLATION.
RX   PubMed=12909353; DOI=10.1016/s0378-1119(03)00614-0;
RA   Vohra P.K., Puri V., Kottom T.J., Limper A.H., Thomas C.F. Jr.;
RT   "Pneumocystis carinii STE11, an HMG-box protein, is phosphorylated by the
RT   mitogen activated protein kinase PCM.";
RL   Gene 312:173-179(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- PTM: Phosphorylated by MAPK2. {ECO:0000269|PubMed:12909353}.
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DR   EMBL; AY257481; AAP13349.1; -; mRNA.
DR   AlphaFoldDB; Q870J1; -.
DR   SMR; Q870J1; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   Gene3D; 1.10.30.10; -; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Nucleus; Phosphoprotein.
FT   CHAIN           1..501
FT                   /note="HMG-box protein STE11"
FT                   /id="PRO_0000247726"
FT   DNA_BIND        201..265
FT                   /note="HMG box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   REGION          142..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          246..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   501 AA;  56647 MW;  A4C36774003DA748 CRC64;
     MLGRDIESDW IGNYWGRDHS LALNTFSKMS IEKEGVLYQK DFFVPYDGLV EELPEHSIEI
     PEIMGQDLLN DRLNSVEDVQ SSYYGRLMPG LNIDLSMPTF PVSNELPVRL SSPIQMNLST
     SMPNPTIEQL HSKTKSYVSQ NPVNMVGSLS GSPPTDCHSP GGNSNTCGTL KTRALSLSPV
     SSDTAAKKKS PSRSGSSSSG IKRPLNSFML YRRDKQSSIP TNNHQSISRI IGEMWKRETI
     EEKERYAEMA QRERERHAKE YPDYKFLPRK KKDRSTSGKS PRRRKTFDPS LEQDESKVLR
     MMLNQISHKK SQSDAEKFKL DQYSWLLSEE GNYDSQKGAF DIICQANTNS SQTGLPHSNQ
     PSEISFIPGI YTAPNSVPLP IFPVKNKVEK VDTHNSLDGY LHTFDNLSDY EFRSLINNHS
     TPSVNDSRLG TSFNKSCTDS PQSISIYDDI KNLDIFSEKK ETPNVSLVPT FDSTIFQDDS
     AYGYDNFTGI WDDPSYRLPV F