ID   STE7_SCHPO              Reviewed;         569 AA.
AC   Q10136;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Protein ste7;
GN   Name=ste7; ORFNames=SPAC23E2.03c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RX   PubMed=10835379; DOI=10.1093/genetics/155.2.539;
RA   Matsuyama A., Yabana N., Watanabe Y., Yamamoto M.;
RT   "Schizosaccharomyces pombe Ste7p is required for both promotion and
RT   withholding of the entry to meiosis.";
RL   Genetics 155:539-549(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Has a role in promoting meiosis whereby it is involved in
CC       establishing the mating pheromone signaling pathway. It also has a role
CC       in suppressing meiosis until the conjugation process is complete.
CC   -!- INDUCTION: By nitrogen starvation.
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; AB036789; BAA90541.1; -; Genomic_DNA.
DR   EMBL; CU329670; CAA93115.3; -; Genomic_DNA.
DR   PIR; T38293; T38293.
DR   RefSeq; NP_592938.1; NM_001018339.2.
DR   AlphaFoldDB; Q10136; -.
DR   BioGRID; 278019; 4.
DR   STRING; 4896.SPAC23E2.03c.1; -.
DR   iPTMnet; Q10136; -.
DR   PaxDb; Q10136; -.
DR   EnsemblFungi; SPAC23E2.03c.1; SPAC23E2.03c.1:pep; SPAC23E2.03c.
DR   GeneID; 2541518; -.
DR   KEGG; spo:SPAC23E2.03c; -.
DR   PomBase; SPAC23E2.03c; ste7.
DR   VEuPathDB; FungiDB:SPAC23E2.03c; -.
DR   HOGENOM; CLU_528023_0_0_1; -.
DR   OMA; GKICFET; -.
DR   PRO; PR:Q10136; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0044732; C:mitotic spindle pole body; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051447; P:negative regulation of meiotic cell cycle; IGI:PomBase.
DR   GO; GO:0031139; P:positive regulation of conjugation with cellular fusion; IMP:PomBase.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
PE   1: Evidence at protein level;
KW   Conjugation; Meiosis; Reference proteome; Stress response.
FT   CHAIN           1..569
FT                   /note="Protein ste7"
FT                   /id="PRO_0000072267"
FT   REGION          195..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          255..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  61102 MW;  FDD23893E9A7A6AC CRC64;
     MFLEIILDSA TYSFDRVITG KICFETNAAT SPRSFQIQLR IKGYAVYHHG FLSSPSHKHP
     TTASASDSDE ATEIFTHSQP LPIPAGPSSK SHAIDFKFKF PSKSASSLPC SKSNDSMVNI
     CYMLKATISK RYAFLGSSQS AKAELIMVPP NLAGKPLSAN SSFGSSAKTF QLPEFDSVTP
     SASLYKQPSF NSNPAPITTS SATHTSQFST SSSSSVNSVH TPVMVPNPYF QYNSSMTAPS
     SSSSSVAPFV PRRQFSVSSA SDPPQTPISM SPPIPPTPSQ FSAFMYQNQQ SYLSPQSHYE
     NPLSISSRPS PCCPSTPSSA VTLSNGFDSQ SNAYNNSGTG PPMLYKFPQR SYTAPNTSFN
     SQRRMSSITS LPTASFCPVK HGVSPPSLAG NQPSPLSSPL TNSNVSPSTI CSPDNNVTFV
     NLAPGEKLTF KIEPNDLMDE EEVVENSNMY SIPGKTVATT VCHSSSSSGD FSALSCHRNL
     SFSESLPTAE DQVHNNHCAV SPSRRSSSNA LYLATLPMGY ERSNSVSYCS DSSLSSPLPD
     DNMLQDPHAL NMAYAKEFDV LINEVLQSL