ID   STEA_SALTY              Reviewed;         210 AA.
AC   Q8ZPD7;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Secreted effector protein SteA;
DE   AltName: Full=Salmonella translocated effector A;
GN   Name=steA; OrderedLocusNames=STM1583;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Effector proteins function to alter host cell physiology and
CC       promote bacterial survival in host tissues. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Note=Secreted via type III secretion systems 1 and 2
CC       (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm.
CC       {ECO:0000250}.
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DR   EMBL; AE006468; AAL20501.1; -; Genomic_DNA.
DR   RefSeq; NP_460542.1; NC_003197.2.
DR   RefSeq; WP_001147134.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZPD7; -.
DR   STRING; 99287.STM1583; -.
DR   PaxDb; Q8ZPD7; -.
DR   EnsemblBacteria; AAL20501; AAL20501; STM1583.
DR   GeneID; 1253101; -.
DR   KEGG; stm:STM1583; -.
DR   PATRIC; fig|99287.12.peg.1674; -.
DR   HOGENOM; CLU_088946_0_0_6; -.
DR   OMA; SFEEICM; -.
DR   BioCyc; SENT99287:STM1583-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host cytoplasm; Reference proteome; Secreted; Virulence.
FT   CHAIN           1..210
FT                   /note="Secreted effector protein SteA"
FT                   /id="PRO_0000391635"
SQ   SEQUENCE   210 AA;  23618 MW;  413279D039731780 CRC64;
     MPYTSVSTYA RALSGNKLPH VAAGDYENKL STKIMKGILY VLTAGLAYGF TRVIEHYCNV
     TPKVAEFCAN AGNIHNHLAD AVRDGLFTID VELSDGRMLT FEQLSLIAEG KPIVRISDGE
     HTVEVEGTFE EICMRLEEGF FEAPAYYDYD IDEKYKTVRE RMAAYNALPQ ALGAIPCLEY
     YIARASNMQE AKAQWAADIK ARYHNYLDNY