ID   STEB_SALT1              Reviewed;         133 AA.
AC   D0ZI38;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Secreted effector protein SteB;
DE   AltName: Full=Salmonella translocated effector B;
GN   Name=steB; OrderedLocusNames=STM14_1970;
OS   Salmonella typhimurium (strain 14028s / SGSC 2262).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=588858;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=14028s / SGSC 2262;
RX   PubMed=19897643; DOI=10.1128/jb.01233-09;
RA   Jarvik T., Smillie C., Groisman E.A., Ochman H.;
RT   "Short-term signatures of evolutionary change in the Salmonella enterica
RT   serovar typhimurium 14028 genome.";
RL   J. Bacteriol. 192:560-567(2010).
RN   [2]
RP   SUBCELLULAR LOCATION, AND SECRETION VIA TYPE III SECRETION SYSTEM.
RX   PubMed=16177297; DOI=10.1128/iai.73.10.6260-6271.2005;
RA   Geddes K., Worley M., Niemann G., Heffron F.;
RT   "Identification of new secreted effectors in Salmonella enterica serovar
RT   Typhimurium.";
RL   Infect. Immun. 73:6260-6271(2005).
CC   -!- FUNCTION: Effector proteins function to alter host cell physiology and
CC       promote bacterial survival in host tissues. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16177297}. Host
CC       cytoplasm {ECO:0000269|PubMed:16177297}. Note=Secreted via type III
CC       secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into
CC       the host cytoplasm.
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DR   EMBL; CP001363; ACY88441.1; -; Genomic_DNA.
DR   RefSeq; WP_001540100.1; NZ_CP043402.1.
DR   AlphaFoldDB; D0ZI38; -.
DR   EnsemblBacteria; ACY88441; ACY88441; STM14_1970.
DR   KEGG; seo:STM14_1970; -.
DR   HOGENOM; CLU_1892472_0_0_6; -.
DR   OMA; GCKEASR; -.
DR   BioCyc; SENT588858:STM14_RS26010-MON; -.
DR   PHI-base; PHI:3750; -.
DR   Proteomes; UP000002695; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host cytoplasm; Secreted; Virulence.
FT   CHAIN           1..133
FT                   /note="Secreted effector protein SteB"
FT                   /id="PRO_0000391638"
SQ   SEQUENCE   133 AA;  14389 MW;  AB2D74BA1266236A CRC64;
     MPISICKHGA PFVVQHENRY GSGASQSSSL SKSIRHISNS HEEIKFISCY SANGACFSNA
     QMLANASGRP VIGYYGKINK LTASLDNSGR IFRPQHKLAA NICYVGNRLL SAPVQLGFGL
     KHLLTCHSNG NVR