STGL4_ARATH
ID STGL4_ARATH Reviewed; 174 AA.
AC Q9C6P6; Q9LPT4;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Stigma-specific STIG1-like protein 4 {ECO:0000303|PubMed:19279211};
DE AltName: Full=Protein KERBEROS {ECO:0000303|PubMed:28696222};
DE Flags: Precursor;
GN Name=KRS {ECO:0000303|PubMed:28696222};
GN OrderedLocusNames=At1g50650 {ECO:0000312|Araport:AT1G50650};
GN ORFNames=F11F12.3 {ECO:0000312|EMBL:AAF87870.1},
GN F17J6.17 {ECO:0000312|EMBL:AAG51203.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=19279211; DOI=10.1073/pnas.0808980106;
RA Wrzaczek M., Brosche M., Kollist H., Kangasjarvi J.;
RT "Arabidopsis GRI is involved in the regulation of cell death induced by
RT extracellular ROS.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5412-5417(2009).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=28696222; DOI=10.1105/tpc.17.00016;
RA Moussu S.A., Doll N.M., Chamot S., Brocard L., Creff A., Fourquin C.,
RA Widiez T., Nimchuk Z.L., Ingram G.C.;
RT "ZHOUPI and KERBEROS mediate embryo/endosperm separation by promoting the
RT formation of an extra-cuticular sheath at the embryo surface.";
RL Plant Cell 29:1642-1656(2017).
CC -!- FUNCTION: Endosperm-specific cysteine-rich protein that acts downstream
CC of BHLH95/ZOU to modify the interface between embryo and endosperm and
CC mediate the separation of these two tissues during seed development.
CC Necessary for the biogenesis of the embryo sheath, an extracuticular
CC endosperm-derived structure at the surface of the embryo. Required for
CC the separation of embryo and endosperm, and for normal progression of
CC the embryo through the endosperm tissue. Required for the formation of
CC a normal embryonic cuticle. {ECO:0000269|PubMed:28696222}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:28696222}.
CC -!- DEVELOPMENTAL STAGE: Specifically expressed in seed endosperm at
CC torpedo stage embryo development. {ECO:0000269|PubMed:28696222}.
CC -!- DISRUPTION PHENOTYPE: Increased embryonic cuticule permeability.
CC Altered cotyledon development. Cup-shaped cotyledons.
CC {ECO:0000269|PubMed:28696222}.
CC -!- SIMILARITY: Belongs to the STIG1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF87870.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC012561; AAF87870.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC079279; AAG51203.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32575.1; -; Genomic_DNA.
DR PIR; B96543; B96543.
DR RefSeq; NP_175480.1; NM_103947.2.
DR AlphaFoldDB; Q9C6P6; -.
DR STRING; 3702.AT1G50650.1; -.
DR PaxDb; Q9C6P6; -.
DR PRIDE; Q9C6P6; -.
DR ProteomicsDB; 228347; -.
DR EnsemblPlants; AT1G50650.1; AT1G50650.1; AT1G50650.
DR GeneID; 841487; -.
DR Gramene; AT1G50650.1; AT1G50650.1; AT1G50650.
DR KEGG; ath:AT1G50650; -.
DR Araport; AT1G50650; -.
DR TAIR; locus:2008006; AT1G50650.
DR eggNOG; ENOG502S2JZ; Eukaryota.
DR HOGENOM; CLU_111795_1_0_1; -.
DR InParanoid; Q9C6P6; -.
DR OMA; GLCGIRC; -.
DR OrthoDB; 1510465at2759; -.
DR PhylomeDB; Q9C6P6; -.
DR PRO; PR:Q9C6P6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C6P6; baseline and differential.
DR Genevisible; Q9C6P6; AT.
DR GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR GO; GO:0042335; P:cuticle development; IMP:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:UniProtKB.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR InterPro; IPR006969; Stig1.
DR PANTHER; PTHR33227; PTHR33227; 1.
DR Pfam; PF04885; Stig1; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..174
FT /note="Stigma-specific STIG1-like protein 4"
FT /evidence="ECO:0000255"
FT /id="PRO_0000431933"
FT REGION 140..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 174 AA; 19531 MW; 04F09A751E6EF7FD CRC64;
MMSIKLTLCA LIFFLLNSLL HHVLGHDNQL NTTSSWLKSH IKAATTTNWG RPKPPMCKPW
ICKRSGPSEA RMRCCRNQCV DVLSDPNHCR FCFKSCRFAL SCCDGDCVDT NTDPSNCGQC
GNECESGAPC EFGMCGYAAP SSQPGKRHRR HKFHRPRPPP SPDSKLNYDD HDDE
