STIL1_ARATH
ID STIL1_ARATH Reviewed; 1116 AA.
AC F4HW65; Q9M9R7;
DT 24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Protein STICHEL-like 1;
GN OrderedLocusNames=At1g14460; ORFNames=F14L17.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. La-0;
RX PubMed=14506206; DOI=10.1074/mcp.t300006-mcp200;
RA Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
RT "Large-scale analysis of in vivo phosphorylated membrane proteins by
RT immobilized metal ion affinity chromatography and mass spectrometry.";
RL Mol. Cell. Proteomics 2:1234-1243(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=12586888; DOI=10.1104/pp.014209;
RA Ilgenfritz H., Bouyer D., Schnittger A., Mathur J., Kirik V., Schwab B.,
RA Chua N.H., Juergens G., Huelskamp M.;
RT "The Arabidopsis STICHEL gene is a regulator of trichome branch number and
RT encodes a novel protein.";
RL Plant Physiol. 131:643-655(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=15308754; DOI=10.1105/tpc.104.023150;
RA Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
RT "Phosphoproteomics of the Arabidopsis plasma membrane and a new
RT phosphorylation site database.";
RL Plant Cell 16:2394-2405(2004).
CC -!- DOMAIN: PEST motif is known to mediate rapid protein degradation.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF43947.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC012188; AAF43947.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29167.1; -; Genomic_DNA.
DR PIR; D86279; D86279.
DR RefSeq; NP_172898.2; NM_101313.3.
DR AlphaFoldDB; F4HW65; -.
DR SMR; F4HW65; -.
DR STRING; 3702.AT1G14460.1; -.
DR iPTMnet; F4HW65; -.
DR PaxDb; F4HW65; -.
DR PRIDE; F4HW65; -.
DR ProteomicsDB; 228298; -.
DR EnsemblPlants; AT1G14460.1; AT1G14460.1; AT1G14460.
DR GeneID; 838008; -.
DR Gramene; AT1G14460.1; AT1G14460.1; AT1G14460.
DR KEGG; ath:AT1G14460; -.
DR Araport; AT1G14460; -.
DR TAIR; locus:2012497; AT1G14460.
DR eggNOG; KOG0989; Eukaryota.
DR HOGENOM; CLU_009072_0_0_1; -.
DR InParanoid; F4HW65; -.
DR OMA; GKRMEHC; -.
DR OrthoDB; 97895at2759; -.
DR PRO; PR:F4HW65; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HW65; baseline and differential.
DR Genevisible; F4HW65; AT.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR022754; DNA_pol_III_gamma-3.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF12169; DNA_pol3_gamma3; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02397; dnaX_nterm; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Coiled coil; Nucleotide-binding; Reference proteome; Repeat.
FT CHAIN 1..1116
FT /note="Protein STICHEL-like 1"
FT /id="PRO_0000422977"
FT REGION 95..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 726..760
FT /evidence="ECO:0000255"
FT MOTIF 257..282
FT /note="PEST 1"
FT /evidence="ECO:0000250"
FT MOTIF 402..422
FT /note="PEST 2"
FT /evidence="ECO:0000250"
FT COMPBIAS 111..126
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 463..470
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1116 AA; 124891 MW; 5BFE62FA10D7E451 CRC64;
MSGLRISDPS KLHLKKELTH IRKVASKGLR DPGTTSSWKS PLTSSRFVVE PPASNNVEIL
SNNQLDSQFP SSRVFGNNGK EKEKKVFLYN WKTQRTSSEK TEGEDETSWI QASLNDDDDD
DDDVSDARNG GDSCLEETRS ASMIRKSGFI KKKSKELDLS IGRKSTAKAR NFPSHHLHVA
SGLSVVRDES DETEDFSNSE NFPTKVSSPL LLKLKRKNWS RSSSKFLRGT SKREDSSHTC
NSTPALSTSS YNMYGIRNPS TVGSWEDGDD ELDDDNLDFK GRQGCGIPFY WTKRNLKHRG
GCRSCCSPSF SDTLRRKGSS ILCGSQSVYR RHRHSSGRFN KQKLALRSAK GVLPLLKYGG
DSRGGSSIGI GYSDDDLSTD FGEIDLEAQS RLDGRRWSSC CKSQDGEREE EEEGGSTPES
IQSLSQKYKP MFFDELIGQS IVVQSLMNAV KKGRVAHVYL FQGPRGTGKT STARILSAAL
NCDVVTEEMK PCGYCKECSD YMLGKSRDLL ELDAGKKNGA EKVRYLLKKL LTLAPQSSQR
YKVFVIDECH LLPSRTWLSL LKFLENPLQK FVFVCITTDL DNVPRTIQSR CQKYIFNKVR
DGDIVVRLRK IASDENLDVE SQALDLIALN ADGSLRDAET MLEQLSLMGK RITVDLVNEL
VGVVSDDKLL ELLELALSSD TAETVKKARE LLDLGADPIL MMSQLASLIM DIIAGAYKAL
DEKYSEAFLD RRNLTEADLE RLKHALKLLS EAEKQLRVST DRSTWFIATL LQLGSMPSPG
TTHTGSSRRQ SSRATEESIS REVIAYKQRS GLQCSNTASP TSIRKSGNLV REVKLSSSSS
EVLESDTSMA SHDDTTASTM TLTCRNSEKL NDIWIKCVDR CHSKTLKQLL YAHGKLLSIS
EVEGILVAYI AFGEGEIKAR AERFVSSITN SIEMVLRRNV EVRIILLSET ELLNSKQTRQ
IAVTTSSYTE SGNEIPMKRI EAIIQEQRLE TEWLQKTPGS QGRLKPERNQ ILPQEDTNGV
KVLKICEMGE FQENQSGKRM EHCPVSPSLL HNSNFTNNKD NLGYESESGR GVCSLLFCWN
TQKSPRRTKI KGTSMRSRRS RERRFSLFSA CARPRK
