STIL2_ARATH
ID STIL2_ARATH Reviewed; 857 AA.
AC F4JRP8; Q9SB72;
DT 24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Protein STICHEL-like 2;
GN OrderedLocusNames=At4g24790; ORFNames=F22K18.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=12586888; DOI=10.1104/pp.014209;
RA Ilgenfritz H., Bouyer D., Schnittger A., Mathur J., Kirik V., Schwab B.,
RA Chua N.H., Juergens G., Huelskamp M.;
RT "The Arabidopsis STICHEL gene is a regulator of trichome branch number and
RT encodes a novel protein.";
RL Plant Physiol. 131:643-655(2003).
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA22984.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79389.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL035356; CAA22984.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161562; CAB79389.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84957.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE84958.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66614.1; -; Genomic_DNA.
DR PIR; T05555; T05555.
DR RefSeq; NP_001119046.1; NM_001125574.2.
DR RefSeq; NP_001328498.1; NM_001341707.1.
DR RefSeq; NP_001328499.1; NM_001341709.1.
DR RefSeq; NP_001328500.1; NM_001341708.1.
DR RefSeq; NP_194210.2; NM_118612.2.
DR AlphaFoldDB; F4JRP8; -.
DR SMR; F4JRP8; -.
DR STRING; 3702.AT4G24790.2; -.
DR iPTMnet; F4JRP8; -.
DR PaxDb; F4JRP8; -.
DR PRIDE; F4JRP8; -.
DR ProteomicsDB; 228412; -.
DR EnsemblPlants; AT4G24790.1; AT4G24790.1; AT4G24790.
DR EnsemblPlants; AT4G24790.2; AT4G24790.2; AT4G24790.
DR EnsemblPlants; AT4G24790.5; AT4G24790.5; AT4G24790.
DR GeneID; 828581; -.
DR Gramene; AT4G24790.1; AT4G24790.1; AT4G24790.
DR Gramene; AT4G24790.2; AT4G24790.2; AT4G24790.
DR Gramene; AT4G24790.5; AT4G24790.5; AT4G24790.
DR KEGG; ath:AT4G24790; -.
DR Araport; AT4G24790; -.
DR TAIR; locus:2121934; AT4G24790.
DR eggNOG; KOG0989; Eukaryota.
DR HOGENOM; CLU_009072_1_0_1; -.
DR InParanoid; F4JRP8; -.
DR OrthoDB; 97895at2759; -.
DR PRO; PR:F4JRP8; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; F4JRP8; baseline and differential.
DR Genevisible; F4JRP8; AT.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02397; dnaX_nterm; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Nucleotide-binding; Reference proteome.
FT CHAIN 1..857
FT /note="Protein STICHEL-like 2"
FT /id="PRO_0000422978"
FT REGION 593..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 544..576
FT /evidence="ECO:0000255"
FT COMPBIAS 593..620
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 280..287
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 857 AA; 93834 MW; 6A44FCA353D6520A CRC64;
MGETRRHSVD VPITRTLVAL RRVRSLRDPC TTSMSKFASL LDNVKWETGS NNGISLQFVE
HADDACKAAA DAPVGLIPFG SYSIMEELES GCDLHKLSSK VINVEGDACS RSSERSCSDL
SVKGRDLACN APSISHVEEA GSGGRYRTHY STKLASSVGE YGSRLGSPMN STNHSYYGDE
DVDFDSQSNR GCGITYCWSR TPRYRGSNQS SDVEEYPLLP GNGNGESDVV TPSHEVLSRS
LSQKFRPKSF DELVGQEVVV KCLLSTILRG RITSVYLFHG PRGTGKTSTS KIFAAALNCL
SQAAHSRPCG LCSECKSYFS GRGRDVMETD SGKLNRPSYL RSLIKSASLP PVSSRFKVFI
IDECQLLCQE TWGTLLNSLD NFSQHSVFIL VTSELEKLPR NVLSRSQKYH FSKVCDADIS
TKLAKICIEE GIDFDQGAVD FIASKSDGSL RDAEIMLDQL SLLGKRITTS LAYKLIGVVS
DDELLDLLDL AMSSDTSNTV IRARELMRSK IDPMQLISQL ANVIMDIIAG NSQESSSATR
LRFLTRHTSE EEMQKLRNAL KILSDAEKHL RASKNQTTWL TVALLQLSNT DSSSFATDEN
GRNQINKDVE LSSTSSGCPG DVIKSDAEKG QERNCNETVE SVWKTVTDLC CSDSLKRFLW
KRGRLTSLTV DKGVAIAELE FYTPQHVARA EKSWKLIADS FQSVLGCNVE IQMNLVISAC
SPPKSAKAAA SLFFGLFSCS RRMLHKSYLT TRTDSDCASE KPAVTNSLRS CQGNVLRARS
VRSSANASSR MSCSSDQGDA TSAMCTPHIP PGEKRPEDDT DVLCWKKTPL GKGQSETQNS
KSSRLIGRVL PCSTAAN
