STIL3_ARATH
ID STIL3_ARATH Reviewed; 1097 AA.
AC F4JRP0; Q9SN33;
DT 24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Protein STICHEL-like 3;
GN OrderedLocusNames=At4g18820; ORFNames=F28A21.230;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=12586888; DOI=10.1104/pp.014209;
RA Ilgenfritz H., Bouyer D., Schnittger A., Mathur J., Kirik V., Schwab B.,
RA Chua N.H., Juergens G., Huelskamp M.;
RT "The Arabidopsis STICHEL gene is a regulator of trichome branch number and
RT encodes a novel protein.";
RL Plant Physiol. 131:643-655(2003).
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB37467.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78884.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL035526; CAB37467.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161549; CAB78884.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84094.1; -; Genomic_DNA.
DR PIR; T04874; T04874.
DR RefSeq; NP_193617.3; NM_117998.4.
DR AlphaFoldDB; F4JRP0; -.
DR SMR; F4JRP0; -.
DR STRING; 3702.AT4G18820.1; -.
DR iPTMnet; F4JRP0; -.
DR PaxDb; F4JRP0; -.
DR PRIDE; F4JRP0; -.
DR ProteomicsDB; 228348; -.
DR EnsemblPlants; AT4G18820.1; AT4G18820.1; AT4G18820.
DR GeneID; 827616; -.
DR Gramene; AT4G18820.1; AT4G18820.1; AT4G18820.
DR KEGG; ath:AT4G18820; -.
DR Araport; AT4G18820; -.
DR TAIR; locus:2124122; AT4G18820.
DR eggNOG; KOG0989; Eukaryota.
DR HOGENOM; CLU_010603_0_0_1; -.
DR InParanoid; F4JRP0; -.
DR OMA; RVENFQA; -.
DR OrthoDB; 97895at2759; -.
DR PRO; PR:F4JRP0; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; F4JRP0; baseline and differential.
DR Genevisible; F4JRP0; AT.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005663; C:DNA replication factor C complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48019; SSF48019; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02397; dnaX_nterm; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Nucleotide-binding; Reference proteome.
FT CHAIN 1..1097
FT /note="Protein STICHEL-like 3"
FT /id="PRO_0000422979"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 790..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 742..770
FT /evidence="ECO:0000255"
FT COMPBIAS 99..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..257
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..430
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 472..479
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1097 AA; 121792 MW; 3428BE2D6F29BEB9 CRC64;
MTTTTTTTTR VASSSSTRNN RILKDANGDI GEHLRNHIHL TNCIHLKNNM HKQSPVLTDR
ALMRDLIVLQ RSRSLRDPSA SPPAWNTPPS VVDLLPKKGD LVEGGRRSVD LKKSSRRLSA
LSGSSPVVNF GTSKVTPSDE RSGPVSGERD SGRRVKREES SRKSYRIGDD YQNVNEVVSH
GSGSKASRRL SRVNDAMVKT LSDQLNEVVV GDSDDVVSSN VRPRVRYGGG GGGGNTRGCA
GGMSRPKRRK FRGTRRVRGK SRDTGGGKSE MSVASNTLPQ VEKHDGEKEG FGEQNMTKAC
GIPFNWSRIH HRGKTFLDKA GRSLSCGMSD SKGGRKGETN ERNGSDKMMI QSDDDSSSFI
GSDGEALPLL VDSGENDGWV HDYSGELGIF ADSLLKNDED SDLASEGRSG EKKHKKKSHV
NARHRHRQQH QSLTEKYTPK TFRDLLGQNL VVQALSNAVA RRKLGLLYVF HGPNGTGKTS
CARIFARALN CHSMEQPKPC GTCSSCVSHD MGKSWNIREV GPVGNYDFEK IMDLLDGNVM
VSSQSPRVFI FDDCDTLSSD CWNALSKVVD RAAPRHVVFI LVCSSLDVLP HVIISRCQKF
FFPKLKDADI VYSLQWIASK EEIEIDKDAL KLIASRSDGS LRDAEMTLEQ LSLLGQRISV
PLVQELVGLV SDEKLVDLLD LALSADTVNT VKNLRTIMET SVEPLALMSQ LATVITDILA
GSYDFTKDQH KRKFFRRQPL PKEDMEKLRQ ALKTLSEAEK QLRVSNDKLT WLTAALLQLA
PDQNYLLQRS STADTGGRES SDHHLDPSSD AAGGRSSGLD RRRGDSRKNR PAVEEIWLEV
IEKLRVNGLR EFLYKEGRIV SLNLGSAPTV HLMFSSPLTK STAEKFRSHI MQAFEAVLES
PVTIEIRCET KKDPRNNVHH HHHHPTVKDK SLPQSLALIG HDYNIDGSGR SEIVEVTESN
GQRRQQQKQQ EEERTEPVGS SALARARRKH LEASQSQNQS QSIVRGKVSL AHVIQQADGC
SLQNGWSKRK AVSIAEKLEQ ENLRLEPRSR SLLCWKSSRG TRRKATRLKV RTRRARPHTL
LKLVSCGKCL STRSPTR
