STKLI_ARATH
ID STKLI_ARATH Reviewed; 414 AA.
AC Q9SJM4; Q6RF62; Q6RF63;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=GLABROUS1 enhancer-binding protein-like 3 {ECO:0000303|PubMed:18162594};
DE AltName: Full=Protein GPL3 {ECO:0000303|PubMed:18162594};
DE AltName: Full=Storekeeper-like protein At2g36340 {ECO:0000305};
GN Name=GPL3 {ECO:0000303|PubMed:18162594};
GN OrderedLocusNames=At2g36340 {ECO:0000312|Araport:AT2G36340};
GN ORFNames=F2H17.5 {ECO:0000312|EMBL:AAD21432.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=12535344; DOI=10.1046/j.1365-313x.2003.01622.x;
RA Curaba J., Herzog M., Vachon G.;
RT "GeBP, the first member of a new gene family in Arabidopsis, encodes a
RT nuclear protein with DNA-binding activity and is regulated by KNAT1.";
RL Plant J. 33:305-317(2003).
RN [7]
RP INTERACTION WITH GEBP; GPL1 AND GPL2, SUBUNIT, SUBCELLULAR LOCATION, AND
RP TISSUE SPECIFICITY.
RX PubMed=18162594; DOI=10.1104/pp.107.110270;
RA Chevalier F., Perazza D., Laporte F., Le Henanff G., Hornitschek P.,
RA Bonneville J.M., Herzog M., Vachon G.;
RT "GeBP and GeBP-like proteins are noncanonical leucine-zipper transcription
RT factors that regulate cytokinin response in Arabidopsis.";
RL Plant Physiol. 146:1142-1154(2008).
RN [8]
RP FUNCTION.
RX PubMed=21875893; DOI=10.1104/pp.111.179804;
RA Perazza D., Laporte F., Balague C., Chevalier F., Remo S., Bourge M.,
RA Larkin J., Herzog M., Vachon G.;
RT "GeBP/GPL transcription factors regulate a subset of CPR5-dependent
RT processes.";
RL Plant Physiol. 157:1232-1242(2011).
RN [9]
RP INTERACTION WITH GEBP.
RX PubMed=29192025; DOI=10.1104/pp.17.01461;
RA Nietzsche M., Guerra T., Alseekh S., Wiermer M., Sonnewald S., Fernie A.R.,
RA Boernke F.;
RT "STOREKEEPER RELATED1/G-element binding protein (STKR1) interacts with
RT protein kinase SnRK1.";
RL Plant Physiol. 176:1773-1792(2018).
CC -!- FUNCTION: Probable transcription factor. Involved in stress responses
CC (PubMed:21875893). Plays a repressive role in cell expansion by
CC counteracting the positive role of CPR5 in this process, but does not
CC regulate cell proliferation or endoreduplication (PubMed:21875893).
CC {ECO:0000269|PubMed:21875893}.
CC -!- SUBUNIT: Homo- and heterodimers. Interacts with GEBP, GPL1 and GPL2.
CC Interacts with GEBP (PubMed:29192025). {ECO:0000269|PubMed:18162594,
CC ECO:0000269|PubMed:29192025}.
CC -!- INTERACTION:
CC Q9SJM4; O82162: EYA; NbExp=3; IntAct=EBI-15199331, EBI-25523010;
CC Q9SJM4; Q9ASZ1: GEBP; NbExp=3; IntAct=EBI-15199331, EBI-15191723;
CC Q9SJM4; Q8VYD2: GPL1; NbExp=3; IntAct=EBI-15199331, EBI-4426914;
CC Q9SJM4; Q9ZSY8: IAA27; NbExp=3; IntAct=EBI-15199331, EBI-3946677;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18162594}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9SJM4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9SJM4-2; Sequence=VSP_058466, VSP_058467;
CC -!- TISSUE SPECIFICITY: Expressed in the apical meristem and young leaf
CC primordia. Detected in the vascular tissues of rosette leaves, in
CC primary and secondary roots and at the base of flowers and siliques.
CC {ECO:0000269|PubMed:18162594}.
CC -!- SIMILARITY: Belongs to the GeBP family. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Plant Transcription Factor Database;
CC URL="http://planttfdb.cbi.pku.edu.cn/family.php?sp=Ath&fam=GeBP#family_intro";
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DR EMBL; AC006921; AAD21432.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09235.1; -; Genomic_DNA.
DR EMBL; AY773863; AAV63892.1; -; mRNA.
DR EMBL; AY501338; AAR99350.2; -; mRNA.
DR EMBL; AY501339; AAR99351.1; -; mRNA.
DR EMBL; AB493578; BAH30416.1; -; mRNA.
DR PIR; E84779; E84779.
DR RefSeq; NP_181175.1; NM_129191.4. [Q9SJM4-1]
DR AlphaFoldDB; Q9SJM4; -.
DR IntAct; Q9SJM4; 9.
DR STRING; 3702.AT2G36340.1; -.
DR iPTMnet; Q9SJM4; -.
DR PaxDb; Q9SJM4; -.
DR PRIDE; Q9SJM4; -.
DR ProteomicsDB; 228301; -. [Q9SJM4-1]
DR EnsemblPlants; AT2G36340.1; AT2G36340.1; AT2G36340. [Q9SJM4-1]
DR GeneID; 818207; -.
DR Gramene; AT2G36340.1; AT2G36340.1; AT2G36340. [Q9SJM4-1]
DR KEGG; ath:AT2G36340; -.
DR Araport; AT2G36340; -.
DR TAIR; locus:2049495; AT2G36340.
DR eggNOG; ENOG502R6TU; Eukaryota.
DR HOGENOM; CLU_055192_0_0_1; -.
DR InParanoid; Q9SJM4; -.
DR OMA; DVPCEEQ; -.
DR OrthoDB; 1195007at2759; -.
DR PhylomeDB; Q9SJM4; -.
DR PRO; PR:Q9SJM4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJM4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR007592; GEBP.
DR PANTHER; PTHR31662; PTHR31662; 1.
DR Pfam; PF04504; DUF573; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..414
FT /note="GLABROUS1 enhancer-binding protein-like 3"
FT /id="PRO_0000436983"
FT REGION 36..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..403
FT /note="Non-canonical leucine-zipper"
FT /evidence="ECO:0000305|PubMed:18162594"
FT VAR_SEQ 159..195
FT /note="YVSNENIDQAKDVPSGEPETNDVPCEEQDDRDVPCEE -> MFLLVSQRLMM
FT CLVRSKTIGMCLVRSKSERISRLIMV (in isoform 2)"
FT /id="VSP_058466"
FT VAR_SEQ 196..414
FT /note="Missing (in isoform 2)"
FT /id="VSP_058467"
SQ SEQUENCE 414 AA; 47339 MW; D35940E2A0A8F4A4 CRC64;
MVGTKRVADS IDTNSDDTLT RNREVEVEAM LSRRKQLRTT TTRTTTTRTT PLSLSSSASK
MNWSKNDELV ILGGIVDYEN ETKLSYRSDW DALYRYIKDC VEAKFSKIQL INKVKNMKRK
FTYNQGRSNH GEQLSFTNTD DDEIFKLSLI IWDKNESEYV SNENIDQAKD VPSGEPETND
VPCEEQDDRD VPCEEQERAN IEIDNGVREK LDQAKDVPCV EQESEDVPCV EQERVSIEID
NGEKEKLDQT MDCEEQENTD VLCEEKGDKD VPCEEQENKD VPCEEQERVS IEIDNGEEEM
SSEEDGVDEV GVMEDTLDSG ISFQGLGKNG VKDKSEEDDV VELGVLQEIF KEDTFFQSLG
RYQQKLLLQN LENVGVERRK ELINEWKALF VDEQRLCVKK LTFAAKLANL GVSP
