STKLM_ARATH
ID STKLM_ARATH Reviewed; 345 AA.
AC Q8LG05;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Transcription factor STKL1 {ECO:0000303|PubMed:27031427};
DE AltName: Full=Protein Storekeeper-like 1 {ECO:0000303|PubMed:27031427};
GN Name=STKL1 {ECO:0000303|PubMed:27031427};
GN OrderedLocusNames=At4g00238 {ECO:0000312|Araport:AT4G00238};
GN ORFNames=F5I10 {ECO:0000312|EMBL:AF195115};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAM61104.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION BY GLUCOSE,
RP AND GENE FAMILY.
RX PubMed=27031427; DOI=10.1016/j.plaphy.2016.03.029;
RA Chung M.S., Lee S., Min J.H., Huang P., Ju H.W., Kim C.S.;
RT "Regulation of Arabidopsis thaliana plasma membrane glucose-responsive
RT regulator (AtPGR) expression by A. thaliana storekeeper-like transcription
RT factor, AtSTKL, modulates glucose response in Arabidopsis.";
RL Plant Physiol. Biochem. 104:155-164(2016).
CC -!- FUNCTION: Transcription repressor that binds DNA in a sequence-specific
CC manner, 5'-GCCT-3', to regulate the expression of PGR. Acts as a
CC modulatory component for the glucose-triggered developmental leaf
CC growth process. {ECO:0000269|PubMed:27031427}.
CC -!- INTERACTION:
CC Q8LG05; Q9LPF0: At1g44810; NbExp=3; IntAct=EBI-4424255, EBI-15194473;
CC Q8LG05; Q9LST3: At5g60142; NbExp=3; IntAct=EBI-4424255, EBI-15192745;
CC Q8LG05; Q05153: SSRP1; NbExp=3; IntAct=EBI-4424255, EBI-15191543;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:27031427}.
CC -!- TISSUE SPECIFICITY: Expressed strongly in leaves and flowers, weakly in
CC roots, and very weakly in stems. {ECO:0000269|PubMed:27031427}.
CC -!- INDUCTION: Up-regulated upon glucose treatment.
CC {ECO:0000269|PubMed:27031427}.
CC -!- SIMILARITY: Belongs to the GeBP family. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Plant Transcription Factor Database;
CC URL="http://planttfdb.cbi.pku.edu.cn/family.php?sp=Ath&fam=GeBP#family_intro";
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DR EMBL; AF195115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE81844.1; -; Genomic_DNA.
DR EMBL; AK118935; BAC43516.1; -; mRNA.
DR EMBL; BT005630; AAO64050.1; -; mRNA.
DR EMBL; AY084536; AAM61104.1; -; mRNA.
DR RefSeq; NP_567159.1; NM_116244.3.
DR AlphaFoldDB; Q8LG05; -.
DR SMR; Q8LG05; -.
DR IntAct; Q8LG05; 9.
DR STRING; 3702.AT4G00238.1; -.
DR iPTMnet; Q8LG05; -.
DR PaxDb; Q8LG05; -.
DR PRIDE; Q8LG05; -.
DR ProteomicsDB; 228419; -.
DR EnsemblPlants; AT4G00238.1; AT4G00238.1; AT4G00238.
DR GeneID; 825892; -.
DR Gramene; AT4G00238.1; AT4G00238.1; AT4G00238.
DR KEGG; ath:AT4G00238; -.
DR Araport; AT4G00238; -.
DR TAIR; locus:505006413; AT4G00238.
DR HOGENOM; CLU_051273_0_0_1; -.
DR InParanoid; Q8LG05; -.
DR OMA; DSEWSNW; -.
DR OrthoDB; 1137098at2759; -.
DR PhylomeDB; Q8LG05; -.
DR PRO; PR:Q8LG05; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8LG05; baseline and differential.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IDA:TAIR.
DR GO; GO:0071333; P:cellular response to glucose stimulus; IMP:TAIR.
DR GO; GO:0010629; P:negative regulation of gene expression; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR007592; GEBP.
DR PANTHER; PTHR31662; PTHR31662; 1.
DR Pfam; PF04504; DUF573; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..345
FT /note="Transcription factor STKL1"
FT /id="PRO_0000436987"
FT REGION 1..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 105
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 345 AA; 38186 MW; 8348D4AFD008105C CRC64;
MASLENPAID SSSEFESSSE EISSSKESKP KEAPVTVPST KTLNSPSAAV AVSDDSESEK
QSFVLTRRKK KEGAAESPAV KSGKKEGAAE SPAVKSGNNE GATESPAVKS GKKRASEGTT
SRDMHVKRIK KEGDNKKGHA QRVWSEEDEI SLLQAMIDFK AETGTSPWDH KDRFFDIAKK
SISFDVSKVQ FFDKIRSFKR KYFGDRKVRS VESDHDKKCL GLAVSFWGSD GVSLETPVKK
KVKDESVLVK ANSKEKNVKP LVKEDEQVVI LGEDSEWFEE SFLVPVIASL GLDEYSVKKK
WSKVSVETKK RIQEKMKLVD AKKCELLLAN MDVLKEVTSV LTQTN
