STLP1_ORYSI
ID STLP1_ORYSI Reviewed; 393 AA.
AC A2WX64;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=Sialyltransferase-like protein 1 {ECO:0000305};
DE EC=2.4.99.- {ECO:0000305};
GN Name=STLP1 {ECO:0000305}; ORFNames=OsI_04506 {ECO:0000312|EMBL:EAY76560.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Possesses sialyltransferase-like activity in vitro. Transfers
CC sialic acid to the oligosaccharide Gal-beta-1,3-GalNAc and to
CC glycoproteins such as asialofetuin, alpha-1-acid glycoprotein (NeuAc-
CC alpha-2,3-Gal-beta-1,3-GalNAc-) and andasialo-alpha-1-acid
CC glycoprotein. The transferred sialic acid is linked to galactose of
CC Gal-beta-1,3-GalNAc through alpha-2,6-linkage.
CC {ECO:0000250|UniProtKB:Q94DD4}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q9SGD2}; Single-pass type II membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC {ECO:0000305}.
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DR EMBL; CM000126; EAY76560.1; -; Genomic_DNA.
DR AlphaFoldDB; A2WX64; -.
DR SMR; A2WX64; -.
DR STRING; 39946.A2WX64; -.
DR EnsemblPlants; BGIOSGA004835-TA; BGIOSGA004835-PA; BGIOSGA004835.
DR Gramene; BGIOSGA004835-TA; BGIOSGA004835-PA; BGIOSGA004835.
DR HOGENOM; CLU_044787_1_0_1; -.
DR OMA; MVCNSSH; -.
DR Proteomes; UP000007015; Chromosome 1.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008373; F:sialyltransferase activity; IEA:EnsemblPlants.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.1480.20; -; 1.
DR InterPro; IPR001675; Glyco_trans_29.
DR InterPro; IPR038578; GT29-like_sf.
DR Pfam; PF00777; Glyco_transf_29; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..393
FT /note="Sialyltransferase-like protein 1"
FT /id="PRO_0000434313"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 9..27
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 28..393
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT CARBOHYD 49
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 212
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 258
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 393 AA; 43512 MW; 6B2B17E29DF77BC0 CRC64;
MKRPLRRPFA VLLFVVLCAA ASFPSVLRRS VGPAPVLAPL PPLDPARLNA TLLRLAAADP
SEAPLRRDVD DLLEGRLPAS SARARAWRLR GDRLHLHLRH HQFPVYRRGH HPDHDHDPLL
HPLPRQELLL DPSLRRALRS WHRLRRHDPG VLRNLPSLLS LPGRIPSCAV VGNSGILLGA
SHGALIDSHA AVFRLNNARI SGFAANVGAK TNLSFINSNV LHLCARRPNC FCHPYGDGVP
ILLYICQAAH FLDVASCNAS SRSLHAASIS VTDPRLDVLC ARIVKYYSLR RFVAETGRAA
EEWSSTRDAA MFHYSSGMQA IMVAVGVCDR VSVFGFGKAA DAKHHYHSNQ KAELDLHDYK
AEYAFYRDLA DRPEVVPFLN DAGIAVPPVV FYH
