STLP3_ORYSI
ID STLP3_ORYSI Reviewed; 384 AA.
AC A2XVC2; Q01IV8;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Sialyltransferase-like protein 3 {ECO:0000305};
DE EC=2.4.99.- {ECO:0000305};
GN Name=STLP3 {ECO:0000305};
GN ORFNames=OsI_16563 {ECO:0000312|EMBL:EAY94782.1},
GN OSIGBa0145C12.8 {ECO:0000312|EMBL:CAH67271.1},
GN OSIGBa0157A06.1 {ECO:0000312|EMBL:CAH67332.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Guang-Lu-Ai No.4;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Possesses sialyltransferase-like activity in vitro. Transfers
CC sialic acid to the glycoprotein asialofetuin. The transferred sialic
CC acid is linked to galactose of Gal-beta-1,3-GalNAc through alpha-2,6-
CC linkage. {ECO:0000250|UniProtKB:Q7FA29}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q9SGD2}; Single-pass type II membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC {ECO:0000305}.
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DR EMBL; CR855184; CAH67271.1; -; Genomic_DNA.
DR EMBL; CR855191; CAH67332.1; -; Genomic_DNA.
DR EMBL; CM000129; EAY94782.1; -; Genomic_DNA.
DR AlphaFoldDB; A2XVC2; -.
DR STRING; 39946.A2XVC2; -.
DR CAZy; GT29; Glycosyltransferase Family 29.
DR EnsemblPlants; BGIOSGA016731-TA; BGIOSGA016731-PA; BGIOSGA016731.
DR Gramene; BGIOSGA016731-TA; BGIOSGA016731-PA; BGIOSGA016731.
DR HOGENOM; CLU_044787_1_0_1; -.
DR OMA; TRHEEGM; -.
DR Proteomes; UP000007015; Chromosome 4.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008373; F:sialyltransferase activity; IEA:EnsemblPlants.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.1480.20; -; 1.
DR InterPro; IPR001675; Glyco_trans_29.
DR InterPro; IPR038578; GT29-like_sf.
DR Pfam; PF00777; Glyco_transf_29; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..384
FT /note="Sialyltransferase-like protein 3"
FT /id="PRO_0000434317"
FT TOPO_DOM 1..5
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 6..26
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..384
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT CARBOHYD 241
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 384 AA; 42000 MW; 665B18CF4C969D07 CRC64;
MKRRHWSHPS CGLLLLVAVF CLLLVFRCSQ LRHSGDGAAA AAPDGGAGRN DGDDVDERLV
ELAAVDPAAM AVLQAAKRLL EGNLARAPER HRDVALRGLR EWVGKQERFD PGVMSELVEL
IKRPIDRYNG DGGGGGEGEG RRYASCAVVG NSGILLAAEH GELIDGHELV VRLNNAPAGD
GRYARHVGAR TGLAFLNSNV LSQCAVPRRG ACFCRAYGEG VPILTYMCNA AHFVEHAVCN
NASSSSSGAA DATAAAPVIV TDPRLDALCA RIVKYYSLRR FARETGRPAE EWARRHEEGM
FHYSSGMQAV VAAAGVCDRV SVFGFGKDAS ARHHYHTLQR RELDLHDYEA EYEFYRDLES
RPEAIPFLRQ RDSGFRLPPV SFYR