STM1_SCHPO
ID STM1_SCHPO Reviewed; 271 AA.
AC Q10482;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Seven transmembrane protein 1;
GN Name=stm1; ORFNames=SPAC17C9.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=ED665;
RX PubMed=11461899; DOI=10.1074/jbc.m100341200;
RA Chung K.-S., Won M., Lee S.-B., Jang Y.-J., Hoe K.-L., Kim D.-U.,
RA Lee J.-W., Kim K.-W., Yoo H.-S.;
RT "Isolation of a novel gene from Schizosaccharomyces pombe: stm1+ encoding a
RT seven-transmembrane loop protein that may couple with the heterotrimeric
RT Galpha 2 protein, Gpa2.";
RL J. Biol. Chem. 276:40190-40201(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-119, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the laat-1 family. {ECO:0000305}.
CC -!- SIMILARITY: To yeast YBR147w and SpAC2E12.03c. {ECO:0000305}.
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DR EMBL; L49134; AAD45180.1; -; mRNA.
DR EMBL; CU329670; CAA97356.1; -; Genomic_DNA.
DR PIR; T11590; T11590.
DR RefSeq; NP_594596.1; NM_001020024.2.
DR AlphaFoldDB; Q10482; -.
DR BioGRID; 278731; 17.
DR STRING; 4896.SPAC17C9.10.1; -.
DR iPTMnet; Q10482; -.
DR PaxDb; Q10482; -.
DR PRIDE; Q10482; -.
DR EnsemblFungi; SPAC17C9.10.1; SPAC17C9.10.1:pep; SPAC17C9.10.
DR GeneID; 2542262; -.
DR KEGG; spo:SPAC17C9.10; -.
DR PomBase; SPAC17C9.10; stm1.
DR VEuPathDB; FungiDB:SPAC17C9.10; -.
DR eggNOG; KOG2913; Eukaryota.
DR HOGENOM; CLU_019699_1_0_1; -.
DR InParanoid; Q10482; -.
DR OMA; ALSLGCW; -.
DR PhylomeDB; Q10482; -.
DR Reactome; R-SPO-5223345; Miscellaneous transport and binding events.
DR PRO; PR:Q10482; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0071627; C:integral component of fungal-type vacuolar membrane; ISO:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IDA:PomBase.
DR GO; GO:0015174; F:basic amino acid transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0034488; P:basic amino acid transmembrane export from vacuole; ISO:PomBase.
DR InterPro; IPR006603; PQ-loop_rpt.
DR Pfam; PF04193; PQ-loop; 2.
DR SMART; SM00679; CTNS; 2.
PE 1: Evidence at protein level;
KW Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..271
FT /note="Seven transmembrane protein 1"
FT /id="PRO_0000072277"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 14..80
FT /note="PQ-loop 1"
FT DOMAIN 185..239
FT /note="PQ-loop 2"
FT MOD_RES 119
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 271 AA; 30614 MW; 3B1BB45072B5AD2A CRC64;
MSVIAPSFDM ANILTELSSF LGALSLGCWV VLLIPQLLEN YKNQSGESIS DLFLIIWLIG
DFFNVLGSIY GNVSSTVLVL SFYYIVSDST LLMQIYYYRW KAARRIASRE HEPLLQSRSL
EEGLHAPIGK QQIWWDRLST RQQFGVMGCV VIVSTIVGNL IISSASSDKS DDDLNAWPFT
AGCISSVLYF CARIPQIIKN HKAKSTEGLS IIFFVLASVG NTSYAFSILV FPASDYLNYT
YANLPWILGA FSTIFLDIYI FYQFIKYRNH Y
