ID   STM2A_XENLA             Reviewed;         178 AA.
AC   Q09001; Q52KY8;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Stathmin-2-A;
DE   AltName: Full=SCG10 protein homolog A;
GN   Name=stmn2-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain;
RX   PubMed=8344928; DOI=10.1016/s0021-9258(19)85437-6;
RA   Maucuer A., Moreau J., Mechali M., Sobel A.;
RT   "Stathmin gene family: phylogenetic conservation and developmental
RT   regulation in Xenopus.";
RL   J. Biol. Chem. 268:16420-16429(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Nervous tissue.
CC   -!- SIMILARITY: Belongs to the stathmin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X71433; CAA50564.1; -; mRNA.
DR   EMBL; BC094138; AAH94138.1; -; mRNA.
DR   PIR; I51642; I51642.
DR   RefSeq; NP_001087990.2; NM_001094521.2.
DR   AlphaFoldDB; Q09001; -.
DR   SMR; Q09001; -.
DR   DNASU; 494676; -.
DR   GeneID; 494676; -.
DR   KEGG; xla:494676; -.
DR   CTD; 494676; -.
DR   Xenbase; XB-GENE-962969; stmn2.L.
DR   OMA; MAFECIL; -.
DR   OrthoDB; 1381987at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 494676; Expressed in brain and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0030426; C:growth cone; ISS:UniProtKB.
DR   GO; GO:0030027; C:lamellipodium; ISS:UniProtKB.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043005; C:neuron projection; ISS:UniProtKB.
DR   GO; GO:0043025; C:neuronal cell body; ISS:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   InterPro; IPR026729; Stathmin-2.
DR   InterPro; IPR030514; Stathmin_CS.
DR   InterPro; IPR000956; Stathmin_fam.
DR   InterPro; IPR036002; Stathmin_sf.
DR   PANTHER; PTHR10104; PTHR10104; 1.
DR   PANTHER; PTHR10104:SF18; PTHR10104:SF18; 1.
DR   Pfam; PF00836; Stathmin; 1.
DR   PIRSF; PIRSF002285; Stathmin; 1.
DR   PRINTS; PR00345; STATHMIN.
DR   SUPFAM; SSF101494; SSF101494; 1.
DR   PROSITE; PS00563; STATHMIN_1; 1.
DR   PROSITE; PS01041; STATHMIN_2; 1.
DR   PROSITE; PS51663; STATHMIN_3; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Coiled coil; Cytoplasm; Membrane; Phosphoprotein;
KW   Reference proteome.
FT   CHAIN           1..178
FT                   /note="Stathmin-2-A"
FT                   /id="PRO_0000182400"
FT   DOMAIN          38..178
FT                   /note="SLD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00998"
FT   COILED          75..178
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   178 AA;  20716 MW;  A5FFBD5CDB6F8A59 CRC64;
     MAKTAIAYKE KMKELSMLSL ICSCFYPEPR NITAYTYDDM EIKQLNKRAS GQAFELILKP
     PSPVSEAPRT LASPKKKDVS LGEIQAKLEA AEDRRKSQEA QILKQLAEKR EHEREVLQKA
     LEENNNFSRM AEEKLILKME QIKENREYYL ASLMERLKEK ERHAAEVRRN KEQLELSG