ID   STMD1_MOUSE             Reviewed;         279 AA.
AC   Q6P3A1;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Stathmin domain-containing protein 1;
GN   Name=Stmnd1; Synonyms=Gm1574;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Thymus;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC153645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC064117; AAH64117.1; -; mRNA.
DR   CCDS; CCDS36650.1; -.
DR   RefSeq; NP_001005422.1; NM_001005422.1.
DR   AlphaFoldDB; Q6P3A1; -.
DR   SMR; Q6P3A1; -.
DR   BioGRID; 237672; 3.
DR   PhosphoSitePlus; Q6P3A1; -.
DR   MaxQB; Q6P3A1; -.
DR   PaxDb; Q6P3A1; -.
DR   PRIDE; Q6P3A1; -.
DR   ProteomicsDB; 258764; -.
DR   Antibodypedia; 77399; 4 antibodies from 4 providers.
DR   Ensembl; ENSMUST00000076622; ENSMUSP00000075923; ENSMUSG00000063529.
DR   GeneID; 380842; -.
DR   KEGG; mmu:380842; -.
DR   UCSC; uc007qhd.1; mouse.
DR   CTD; 401236; -.
DR   MGI; MGI:2686420; Stmnd1.
DR   VEuPathDB; HostDB:ENSMUSG00000063529; -.
DR   eggNOG; ENOG502S3US; Eukaryota.
DR   GeneTree; ENSGT01030000234597; -.
DR   HOGENOM; CLU_089666_0_0_1; -.
DR   InParanoid; Q6P3A1; -.
DR   OMA; SYNQEDD; -.
DR   OrthoDB; 1164440at2759; -.
DR   PhylomeDB; Q6P3A1; -.
DR   TreeFam; TF333434; -.
DR   BioGRID-ORCS; 380842; 3 hits in 72 CRISPR screens.
DR   PRO; PR:Q6P3A1; -.
DR   Proteomes; UP000000589; Chromosome 13.
DR   RNAct; Q6P3A1; protein.
DR   Bgee; ENSMUSG00000063529; Expressed in olfactory epithelium and 43 other tissues.
DR   Genevisible; Q6P3A1; MM.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR   GO; GO:0015631; F:tubulin binding; IBA:GO_Central.
DR   GO; GO:0007019; P:microtubule depolymerization; IBA:GO_Central.
DR   GO; GO:0031175; P:neuron projection development; IBA:GO_Central.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IBA:GO_Central.
DR   InterPro; IPR000956; Stathmin_fam.
DR   InterPro; IPR036002; Stathmin_sf.
DR   PANTHER; PTHR10104; PTHR10104; 1.
DR   SUPFAM; SSF101494; SSF101494; 1.
DR   PROSITE; PS51663; STATHMIN_3; 1.
PE   2: Evidence at transcript level;
KW   Lipoprotein; Myristate; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..279
FT                   /note="Stathmin domain-containing protein 1"
FT                   /id="PRO_0000421694"
FT   DOMAIN          121..248
FT                   /note="SLD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00998"
FT   REGION          1..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          178..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..198
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   279 AA;  31413 MW;  5A0CCE2E2CDC5229 CRC64;
     MGCGPSQQKE DQSQSRIPSP RKGWEEGSKA DVRVTSSKEN CSPQTEAAWP KHTIDNAKSL
     DQQAQIGSLP GTIPENSPTP SKTSRRINSD PVANGLTNKP QLPESWERPK SSDILEELIV
     QGIIQSRSKV FRNGESYDVM VDTTEKPLRK PPARLKKLKV KKEVKDFTIQ DIEEKMQAAE
     ERRKTKKEEI RKRLRSDRLL PTANPSDEAE PPGRVEVPFT KGLPAVNTPA LEKSDVQEGE
     PLKRKKSESD VAQMNRNYSC TGLELVESDM YYNQEDNIF