ID   STO1_CAEEL              Reviewed;         330 AA.
AC   Q19200;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   27-MAY-2002, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Stomatin-1;
GN   Name=sto-1; ORFNames=F08C6.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. {ECO:0000305}.
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DR   EMBL; FO080866; CCD67347.1; -; Genomic_DNA.
DR   PIR; T15971; T15971.
DR   RefSeq; NP_509281.1; NM_076880.5.
DR   AlphaFoldDB; Q19200; -.
DR   SMR; Q19200; -.
DR   STRING; 6239.F08C6.4a; -.
DR   EPD; Q19200; -.
DR   PaxDb; Q19200; -.
DR   PeptideAtlas; Q19200; -.
DR   EnsemblMetazoa; F08C6.4a.1; F08C6.4a.1; WBGene00006063.
DR   GeneID; 181017; -.
DR   UCSC; F08C6.4b; c. elegans.
DR   CTD; 181017; -.
DR   WormBase; F08C6.4a; CE27924; WBGene00006063; sto-1.
DR   eggNOG; KOG2621; Eukaryota.
DR   GeneTree; ENSGT01030000234614; -.
DR   InParanoid; Q19200; -.
DR   OMA; HCPISSV; -.
DR   OrthoDB; 1062075at2759; -.
DR   PhylomeDB; Q19200; -.
DR   PRO; PR:Q19200; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00006063; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   ExpressionAtlas; Q19200; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR043202; Band-7_stomatin-like.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR018080; Band_7/stomatin-like_CS.
DR   InterPro; IPR028513; Stomatin-1.
DR   InterPro; IPR001972; Stomatin_HflK_HflKC_fam.
DR   PANTHER; PTHR10264; PTHR10264; 1.
DR   PANTHER; PTHR10264:SF113; PTHR10264:SF113; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PRINTS; PR00721; STOMATIN.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   PROSITE; PS01270; BAND_7; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..330
FT                   /note="Stomatin-1"
FT                   /id="PRO_0000094039"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   330 AA;  35838 MW;  45E63234F5E35242 CRC64;
     MQPSETVEMQ EMAQPSGQQR DVEARVQSAP ANHSHDAGCT EMFCIAMSYV LIFLTFPVSV
     FMCIKIVQEY QRAVVFRLGR LVPDVKGPGI FFIIPCIDTF LNIDLRVASY NVPSQEILSR
     DSVTVSVDAV VYFKVFDPIT SVVGVGNATD STKLLAQTTL RTILGTHTLS EILSDREKIS
     ADMKISLDEA TEPWGIKVER VELRDVRLPS QMQRAMAAEA EATRDAGAKI IAAEGELRAS
     AALAEAATII SKSEGAMQLR YLHTLNAISS EKTSTIIFPF PMEILGGISK VGSGGTSQNF
     PVQEMMNAAL QSIQRQDTVP ATASSSGSRL