STP3_PIG
ID STP3_PIG Reviewed; 76 AA.
AC Q7M2P1;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Spermatid nuclear transition protein 3;
DE Short=STP-3;
DE Short=TP-3;
DE Short=TP3;
GN Name=TNP3;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Spermatid;
RX PubMed=8188637; DOI=10.1093/oxfordjournals.jbchem.a124305;
RA Akama K., Oka S., Tobita T., Hayashi H.;
RT "The amino acid sequence of a boar transition protein 3.";
RL J. Biochem. 115:58-65(1994).
CC -!- FUNCTION: Involved in nuclear basic protein transition: histones are
CC replaced by spermatid specific proteins which are themselves replaced
CC by protamines in late spermatids.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
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DR PIR; JX0304; JX0304.
DR AlphaFoldDB; Q7M2P1; -.
DR SMR; Q7M2P1; -.
DR PRIDE; Q7M2P1; -.
DR OMA; TTNTKRW; -.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Unplaced.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA-binding; Nucleosome core; Nucleus;
KW Reference proteome; Spermatogenesis.
FT CHAIN 1..76
FT /note="Spermatid nuclear transition protein 3"
FT /id="PRO_0000191434"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..34
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 76 AA; 9134 MW; A7E55C008C49EEE2 CRC64;
AKVTEKSWQP QTTSTKRWKK RKTPSQPRSR GKVRKIYKKV KRPLHVCSRK KYSPKVITTS
RRQKRARRAN KFETIP