ID   STP3_SHEEP              Reviewed;         110 AA.
AC   O97965;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Spermatid nuclear transition protein 3;
DE            Short=STP-3;
DE            Short=TP-3;
DE            Short=TP3;
DE   AltName: Full=Spermatidal protein 3;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND PROTEIN SEQUENCE OF 2-110.
RC   TISSUE=Testis;
RX   PubMed=9874212; DOI=10.1046/j.1432-1327.1998.2580460.x;
RA   Chevaillier P., Chirat F., Sautiere P.;
RT   "The amino acid sequence of the ram spermatidal protein 3 -- a transition
RT   protein TP3 or TP4?";
RL   Eur. J. Biochem. 258:460-464(1998).
CC   -!- FUNCTION: Involved in nuclear basic protein transition: histones are
CC       replaced by spermatid specific proteins which are themselves replaced
CC       by protamines in late spermatids.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
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DR   EMBL; Y18266; CAA77097.1; -; Genomic_DNA.
DR   EMBL; AF078926; AAD09749.1; -; mRNA.
DR   RefSeq; NP_001009730.1; NM_001009730.1.
DR   AlphaFoldDB; O97965; -.
DR   PRIDE; O97965; -.
DR   GeneID; 443035; -.
DR   KEGG; oas:443035; -.
DR   eggNOG; ENOG502TD5A; Eukaryota.
DR   OrthoDB; 1541808at2759; -.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR040433; Spermatid_TP.
DR   PANTHER; PTHR37876; PTHR37876; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA-binding; Nucleosome core; Nucleus;
KW   Reference proteome; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:9874212"
FT   CHAIN           2..110
FT                   /note="Spermatid nuclear transition protein 3"
FT                   /id="PRO_0000191435"
FT   REGION          80..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   110 AA;  13331 MW;  AB186EB341905145 CRC64;
     MAKGTRKPRQ PRRVAVRFAS RMKGRKKTLW QRRYRGSVKA PNMTMRVRRP LKGTLRKKIR
     SYATPSKKVK NTREPNCFLR SCAREKLNQS RKRYQNMRQS QRRGQNQKRR