STPG1_XENLA
ID STPG1_XENLA Reviewed; 352 AA.
AC Q3KQ80;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 40.
DE RecName: Full=O(6)-methylguanine-induced apoptosis 2;
DE Short=MAPO2;
DE AltName: Full=Sperm-tail PG-rich repeat-containing protein 1;
GN Name=stpg1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May positively contribute to the induction of apoptosis
CC triggered by O(6)-methylguanine. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the STPG1 family. {ECO:0000305}.
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DR EMBL; BC106348; AAI06349.1; -; mRNA.
DR RefSeq; NP_001089693.1; NM_001096224.1.
DR RefSeq; XP_018100817.1; XM_018245328.1.
DR RefSeq; XP_018100818.1; XM_018245329.1.
DR AlphaFoldDB; Q3KQ80; -.
DR DNASU; 734755; -.
DR GeneID; 734755; -.
DR KEGG; xla:734755; -.
DR CTD; 734755; -.
DR Xenbase; XB-GENE-6255286; stpg1.L.
DR OMA; GQYENPI; -.
DR OrthoDB; 1516381at2759; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 734755; Expressed in testis and 12 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR InterPro; IPR010736; SHIPPO-rpt.
DR Pfam; PF07004; SHIPPO-rpt; 4.
PE 2: Evidence at transcript level;
KW Apoptosis; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..352
FT /note="O(6)-methylguanine-induced apoptosis 2"
FT /id="PRO_0000305174"
FT REPEAT 80..90
FT /note="STPGR 1"
FT REPEAT 124..139
FT /note="STPGR 2"
FT REPEAT 165..171
FT /note="STPGR 3"
FT REPEAT 205..235
FT /note="STPGR 4"
FT REPEAT 244..263
FT /note="STPGR 5"
FT REPEAT 286..295
FT /note="STPGR 6"
FT REPEAT 325..335
FT /note="STPGR 7"
SQ SEQUENCE 352 AA; 38907 MW; A0D4337397583A55 CRC64;
MDFHIRNSNL QEIEVRRKPH SRSPKIQQTE AEATAMNFRI PATASSIPTK YQTVFIPTSE
KNGFNSRSLR FSYSLTQNEN PGPGAYNVAR TSADINSVSL SKKGTGGFPS KAPRTLQCKI
ARTPAPNAYN VYEEFFSKKD FSKGNSSMFQ QPIAMEVEDT NHLTPAPNQY SASLTYCHPN
NNVSAHAAFV SKTKRELLKP NPVKGPSPCH YKINDSLVKE STKVPVSCFK SKTSRNSLNV
ISDNPGPASY DPYKSSESEK KIIFLRKHYL CFSAPAMPIP KAPPVPGPGH YDIVDYEGLP
KQYMSGAAFV SNTSRWAGDV SGKSLPGPGA YHPEIPGRYS FLYNSNRKWV PA