ID   STPG2_HUMAN             Reviewed;         459 AA.
AC   Q8N412;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Sperm-tail PG-rich repeat-containing protein 2;
GN   Name=STPG2; Synonyms=C4orf37;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Pancreas;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; CH471057; EAX06067.1; -; Genomic_DNA.
DR   EMBL; BC036870; AAH36870.1; -; mRNA.
DR   CCDS; CCDS3645.1; -.
DR   RefSeq; NP_777612.1; NM_174952.2.
DR   AlphaFoldDB; Q8N412; -.
DR   BioGRID; 130143; 7.
DR   IntAct; Q8N412; 3.
DR   STRING; 9606.ENSP00000295268; -.
DR   GlyConnect; 1767; 1 N-Linked glycan (1 site).
DR   GlyGen; Q8N412; 1 site, 1 N-linked glycan (1 site).
DR   iPTMnet; Q8N412; -.
DR   PhosphoSitePlus; Q8N412; -.
DR   BioMuta; STPG2; -.
DR   DMDM; 74728806; -.
DR   PaxDb; Q8N412; -.
DR   PeptideAtlas; Q8N412; -.
DR   PRIDE; Q8N412; -.
DR   Antibodypedia; 67933; 26 antibodies from 7 providers.
DR   DNASU; 285555; -.
DR   Ensembl; ENST00000295268.4; ENSP00000295268.3; ENSG00000163116.10.
DR   GeneID; 285555; -.
DR   KEGG; hsa:285555; -.
DR   MANE-Select; ENST00000295268.4; ENSP00000295268.3; NM_174952.3; NP_777612.1.
DR   UCSC; uc003htt.3; human.
DR   CTD; 285555; -.
DR   DisGeNET; 285555; -.
DR   GeneCards; STPG2; -.
DR   HGNC; HGNC:28712; STPG2.
DR   HPA; ENSG00000163116; Tissue enhanced (brain, testis).
DR   neXtProt; NX_Q8N412; -.
DR   OpenTargets; ENSG00000163116; -.
DR   PharmGKB; PA162379799; -.
DR   VEuPathDB; HostDB:ENSG00000163116; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   GeneTree; ENSGT00390000001063; -.
DR   HOGENOM; CLU_040300_1_0_1; -.
DR   InParanoid; Q8N412; -.
DR   OMA; KTSYYEN; -.
DR   OrthoDB; 710636at2759; -.
DR   PhylomeDB; Q8N412; -.
DR   TreeFam; TF328881; -.
DR   PathwayCommons; Q8N412; -.
DR   SignaLink; Q8N412; -.
DR   BioGRID-ORCS; 285555; 7 hits in 1066 CRISPR screens.
DR   ChiTaRS; STPG2; human.
DR   GenomeRNAi; 285555; -.
DR   Pharos; Q8N412; Tdark.
DR   PRO; PR:Q8N412; -.
DR   Proteomes; UP000005640; Chromosome 4.
DR   RNAct; Q8N412; protein.
DR   Bgee; ENSG00000163116; Expressed in buccal mucosa cell and 78 other tissues.
DR   ExpressionAtlas; Q8N412; baseline and differential.
DR   Genevisible; Q8N412; HS.
DR   InterPro; IPR010736; SHIPPO-rpt.
DR   Pfam; PF07004; SHIPPO-rpt; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..459
FT                   /note="Sperm-tail PG-rich repeat-containing protein 2"
FT                   /id="PRO_0000311960"
FT   REPEAT          21..30
FT                   /note="STPGR 1"
FT   REPEAT          63..73
FT                   /note="STPGR 2"
FT   REPEAT          119..148
FT                   /note="STPGR 3"
FT   REPEAT          157..203
FT                   /note="STPGR 4"
FT   REPEAT          213..243
FT                   /note="STPGR 5"
FT   REPEAT          257..268
FT                   /note="STPGR 6"
FT   REPEAT          351..377
FT                   /note="STPGR 7"
FT   REPEAT          400..410
FT                   /note="STPGR 8"
FT   REPEAT          433..443
FT                   /note="STPGR 9"
FT   VARIANT         111
FT                   /note="C -> W (in dbSNP:rs13131259)"
FT                   /id="VAR_037359"
FT   VARIANT         112
FT                   /note="F -> V (in dbSNP:rs13131258)"
FT                   /id="VAR_037360"
FT   VARIANT         125
FT                   /note="Y -> H (in dbSNP:rs17558193)"
FT                   /id="VAR_037361"
FT   VARIANT         178
FT                   /note="I -> V (in dbSNP:rs2903150)"
FT                   /id="VAR_037362"
FT   VARIANT         279
FT                   /note="K -> R (in dbSNP:rs7654193)"
FT                   /id="VAR_037363"
FT   VARIANT         420
FT                   /note="V -> A (in dbSNP:rs17026871)"
FT                   /id="VAR_037364"
SQ   SEQUENCE   459 AA;  50660 MW;  17CA66DA1237B534 CRC64;
     MYDRAPRLLK LAEGGSTEAH VGPGSYQVPF LKQQATGSNA PFLSLTARES TFTIASSIEK
     AVPGPGHYNV SEAQKISRSP TLTRSVDVPS IPSCGKSYGY HINDDGSIIK CFPPACDSTL
     GPAYYKPQFD VSNATLKYKG IHFGNSSGRQ ELPKKSGPGP GQYDIVQKKT SYYENVNIKR
     DQQQNYCSFI PRLYEIIVLQ EKKKRFLPMK SITPAPGTYN EPRTALKSLK KTSGLKNIPF
     GQSAVRFTQD IRTEEMPGPG FYNVLNNTII ASVRNICSKK QKKSAFGSSV PRTFFSVQKE
     ACATPGPADY QEFWHSQGVG ISDELPNLTN KYAAFLSRAK RTMKVPDMVI PAPGSYDVHK
     SYEMSQVKHK YMPPRSLVAK RKHASFLSAT PRCLEKVTDG PGPAAYNPVL RKSCPIPLFV
     KASKRFEESK EITPGPATYE ISQEKKKGNL IGEMAADIM