ID   STRBP_CHICK             Reviewed;         672 AA.
AC   Q5ZIL4;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Spermatid perinuclear RNA-binding protein;
GN   Name=STRBP; ORFNames=RCJMB04_25e3;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May be involved in normal spermatogenesis and sperm function.
CC       Binds to double-stranded DNA and RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AJ720770; CAG32429.1; -; mRNA.
DR   RefSeq; NP_001025851.1; NM_001030680.1.
DR   AlphaFoldDB; Q5ZIL4; -.
DR   SMR; Q5ZIL4; -.
DR   STRING; 9031.ENSGALP00000001800; -.
DR   PaxDb; Q5ZIL4; -.
DR   Ensembl; ENSGALT00000083865; ENSGALP00000064181; ENSGALG00000029927.
DR   GeneID; 417105; -.
DR   KEGG; gga:417105; -.
DR   CTD; 55342; -.
DR   VEuPathDB; HostDB:geneid_417105; -.
DR   eggNOG; KOG3792; Eukaryota.
DR   GeneTree; ENSGT00940000154687; -.
DR   HOGENOM; CLU_015490_1_0_1; -.
DR   InParanoid; Q5ZIL4; -.
DR   OrthoDB; 612611at2759; -.
DR   PhylomeDB; Q5ZIL4; -.
DR   PRO; PR:Q5ZIL4; -.
DR   Proteomes; UP000000539; Chromosome 17.
DR   Bgee; ENSGALG00000029927; Expressed in ovary and 13 other tissues.
DR   ExpressionAtlas; Q5ZIL4; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR   GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   CDD; cd19909; DSRM_STRBP_rpt1; 1.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR006561; DZF_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR030446; STRBP.
DR   InterPro; IPR044472; STRBP_DSRM_1.
DR   PANTHER; PTHR45762:SF1; PTHR45762:SF1; 3.
DR   Pfam; PF00035; dsrm; 2.
DR   Pfam; PF07528; DZF; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SMART; SM00572; DZF; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
DR   PROSITE; PS51703; DZF; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Developmental protein; Differentiation; DNA-binding;
KW   Reference proteome; Repeat; RNA-binding; Spermatogenesis.
FT   CHAIN           1..672
FT                   /note="Spermatid perinuclear RNA-binding protein"
FT                   /id="PRO_0000274921"
FT   DOMAIN          5..362
FT                   /note="DZF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01040"
FT   DOMAIN          386..452
FT                   /note="DRBM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT   DOMAIN          509..575
FT                   /note="DRBM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT   REGION          348..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..494
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   672 AA;  73372 MW;  38580F3532DF0F08 CRC64;
     MRSIRSFAND DRHVMVKHST IYPSPEELEA VQNMVSTVEC ALKHVSDWMD EKNKSVKCEG
     DVEAKEEAAE SNAKDQSGRT LCGVMRIGLV AKGLLIKDDM DLELVLMCKE KPTKTLLCIV
     KDNLPIQIQK LTEEKYLVEE HVNEAAIIIR NTKEPKLTLK VILTSPLIRD EAEKKEGDSV
     AMKDPPDLLD RQKCLEALAS LRHAKWFQAR ANGLKSCVIV LRILRDLCNR VPTWAPLKGW
     PLELICEKSI GTCNRPLGAG EALRRVMECL ASGILLPGGP GLHDPCEREP TDALSDMTVQ
     QKEAITHSAQ HALRLSAFGQ IYKVLEMDPL PSNKSFQKYS WSVADKEGTG SSALKRPFED
     GVGDDKDPNK KMKRNLRKIL DSKAIDLMNA LMRLNQIRPG LQYKLLSQSG PVHAPVFTMS
     VDVDGTTYEA SGPSKKTAKL HVAVKVLQAM GYPTGFDADV ECVSSDEKSD NEGKNETVSS
     ISSNNTGNST ADTSATLEVR TQGPILTASG KNPVMELNEK RRGLKYELIS ETGGSHDKRF
     VMEVEVDGQK FRGAGPNKKV AKASAALAAL EKLFSGPNAA NNKKKKILPQ QTKGVVNTAV
     SAAVQAVRGR GRGALTRGAF VGAAAATGYI TPGYGAPYGY STAAPAYGLP KRMVLLPVMK
     FPTYPVPHYS FF