ID   STRBP_XENLA             Reviewed;         686 AA.
AC   Q6DCD0;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Spermatid perinuclear RNA-binding protein;
GN   Name=strbp;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in spermatogenesis and sperm function. Binds
CC       to double-stranded DNA and RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BC078118; AAH78118.1; -; mRNA.
DR   RefSeq; NP_001087171.1; NM_001093702.1.
DR   AlphaFoldDB; Q6DCD0; -.
DR   SMR; Q6DCD0; -.
DR   DNASU; 447060; -.
DR   GeneID; 447060; -.
DR   KEGG; xla:447060; -.
DR   CTD; 447060; -.
DR   Xenbase; XB-GENE-1005089; strbp.L.
DR   OrthoDB; 612611at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 447060; Expressed in egg cell and 16 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   CDD; cd19909; DSRM_STRBP_rpt1; 1.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR006561; DZF_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR030446; STRBP.
DR   InterPro; IPR044472; STRBP_DSRM_1.
DR   PANTHER; PTHR45762:SF1; PTHR45762:SF1; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   Pfam; PF07528; DZF; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SMART; SM00572; DZF; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
DR   PROSITE; PS51703; DZF; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Developmental protein; Differentiation; DNA-binding;
KW   Reference proteome; Repeat; RNA-binding; Spermatogenesis.
FT   CHAIN           1..686
FT                   /note="Spermatid perinuclear RNA-binding protein"
FT                   /id="PRO_0000274922"
FT   DOMAIN          5..360
FT                   /note="DZF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01040"
FT   DOMAIN          387..453
FT                   /note="DRBM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT   DOMAIN          509..575
FT                   /note="DRBM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT   REGION          339..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          464..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        350..368
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..498
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  75304 MW;  978542A84D05B36E CRC64;
     MRSIRSFAND DRHVMAKHSI IYPSPEELEA VQNMVSTVES ALKQVSDWID EQKCTKIENG
     SPIKNESTED SSAKDESGKV LCGVMRIGLV AKGLLIKDDM DLELVLLCKE KPSTRLLTTV
     AENLPLQIQK ITEETFQVEQ CVEESSLLIQ SSKEPKLTLK VILSSPLFRE EEERPGGVEN
     VAMKDPPDLL DRQKCLNALA SLRHAKWFQA RANGLKSCVI VLRILRDLCN RVPTWAQLKG
     WPLELICEKA IGTCNRPLGA GEALRRVMEC LAFGTLLPGG SGLHDPCEKE PTDALAYMTV
     KEREEITHSA QHALRLLAFG QIYKVLQMDP LPSNKPFQKY SWSNSDREGS CLKRPFDDGS
     SDEKDPNKKL KRNLSKILDS KPIDPNQPMN ALMRLNQIRP GLQYKLLSQS GPVHAPVFTM
     SVDVDGTTHE ASGPSKKTAK LYVTVKVLQA MGYPTGFDTD LECLSSDEKS DSEGKNETSF
     SSSSNITGNS NADNNTLEVR TQGPILTASG KNPVMELNEK RRGLKYELIS ESGGSHDKRF
     IMEVEVDAQK FKGAGPNKKV AKASAALAAL EKLFSGPNAV NNKKKKIIPQ TKGVVSTAVS
     AAVQAARGRG RVAMARGAFV GATAAAAPGY IAPGMRREEM HPEIFNGYAA PYAYSAATPA
     YGIPKRMVLL PVMKFPAYPV PHYSFF