ABI4_ARATH
ID ABI4_ARATH Reviewed; 328 AA.
AC A0MES8; O81138; Q6J9N5;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Ethylene-responsive transcription factor ABI4 {ECO:0000303|PubMed:9634591};
DE Short=ERF ABI4 {ECO:0000303|PubMed:9634591};
DE AltName: Full=Protein ABSCISIC ACID INSENSITIVE 4 {ECO:0000303|PubMed:9634591};
DE AltName: Full=Protein GLUCOSE INSENSITIVE 6 {ECO:0000303|PubMed:10950871};
DE AltName: Full=Protein IMPAIRED SUCROSE INDUCTION 3 {ECO:0000303|PubMed:11439129};
DE AltName: Full=Protein SALOBRENO 5 {ECO:0000303|PubMed:10629000};
DE AltName: Full=Protein SUCROSE UNCOUPLED 6 {ECO:0000303|PubMed:9144963};
DE AltName: Full=Protein SUGAR INSENSITIVE 5 {ECO:0000303|PubMed:10972885};
GN Name=ABI4 {ECO:0000303|PubMed:9634591};
GN Synonyms=ERF052, GIN6 {ECO:0000303|PubMed:10950871},
GN ISI3 {ECO:0000303|PubMed:11439129}, SAN5 {ECO:0000303|PubMed:10629000},
GN SIS5 {ECO:0000303|PubMed:10972885}, SUN6 {ECO:0000303|PubMed:9144963};
GN OrderedLocusNames=At2g40220 {ECO:0000312|Araport:AT2G40220};
GN ORFNames=T7M7.16 {ECO:0000312|EMBL:AAD25937.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=9634591; DOI=10.2307/3870689;
RA Finkelstein R.R., Wang M.L., Lynch T.J., Rao S., Goodman H.M.;
RT "The Arabidopsis abscisic acid response locus ABI4 encodes an APETALA 2
RT domain protein.";
RL Plant Cell 10:1043-1054(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10207155;
RA Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.;
RT "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07.";
RL Genome Res. 9:325-333(1999).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [7]
RP FUNCTION.
RX PubMed=9144963; DOI=10.2307/3870509;
RA Dijkwel P.P., Huijser C., Weisbeek P.J., Chua N.-H., Smeekens S.C.M.;
RT "Sucrose control of phytochrome A signaling in Arabidopsis.";
RL Plant Cell 9:583-595(1997).
RN [8]
RP FUNCTION.
RX PubMed=9418043; DOI=10.1046/j.1365-313x.1997.12051011.x;
RA Van Oosten J.-J.M., Gerbaud A., Huijser C., Dijkwel P.P., Chua N.-H.,
RA Smeekens S.C.M.;
RT "An Arabidopsis mutant showing reduced feedback inhibition of
RT photosynthesis.";
RL Plant J. 12:1011-1020(1997).
RN [9]
RP FUNCTION.
RX PubMed=10629000; DOI=10.1093/genetics/154.1.421;
RA Quesada V., Ponce M.R., Micol J.L.;
RT "Genetic analysis of salt-tolerant mutants in Arabidopsis thaliana.";
RL Genetics 154:421-436(2000).
RN [10]
RP FUNCTION.
RX PubMed=10950871;
RA Arenas-Huertero F., Arroyo A., Zhou L., Sheen J., Leon P.;
RT "Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6,
RT reveals a central role of the plant hormone ABA in the regulation of plant
RT vegetative development by sugar.";
RL Genes Dev. 14:2085-2096(2000).
RN [11]
RP FUNCTION, DEVELOPMENTAL STAGE, AND TISSUE SPECIFICITY.
RX PubMed=11115891; DOI=10.1104/pp.124.4.1752;
RA Soederman E.M., Brocard I.M., Lynch T.J., Finkelstein R.R.;
RT "Regulation and function of the Arabidopsis ABA-insensitive4 gene in seed
RT and abscisic acid response signaling networks.";
RL Plant Physiol. 124:1752-1765(2000).
RN [12]
RP FUNCTION.
RX PubMed=10972884; DOI=10.1046/j.1365-313x.2000.00822.x;
RA Huijser C., Kortstee A., Pego J., Weisbeek P.J., Wisman E., Smeekens S.;
RT "The Arabidopsis SUCROSE UNCOUPLED-6 gene is identical to ABSCISIC ACID
RT INSENSITIVE-4: involvement of abscisic acid in sugar responses.";
RL Plant J. 23:577-585(2000).
RN [13]
RP FUNCTION, AND MUTAGENESIS OF GLU-69.
RX PubMed=10972885; DOI=10.1046/j.1365-313x.2000.00833.x;
RA Laby R.J., Kincaid M.S., Kim D., Gibson S.I.;
RT "The Arabidopsis sugar-insensitive mutants sis4 and sis5 are defective in
RT abscisic acid synthesis and response.";
RL Plant J. 23:587-596(2000).
RN [14]
RP FUNCTION, AND MUTAGENESIS OF GLU-69.
RX PubMed=11439129; DOI=10.1046/j.1365-313x.2001.2641043.x;
RA Rook F., Corke F., Card R., Munz G., Smith C., Bevan M.W.;
RT "Impaired sucrose-induction mutants reveal the modulation of sugar-induced
RT starch biosynthetic gene expression by abscisic acid signalling.";
RL Plant J. 26:421-433(2001).
RN [15]
RP FUNCTION.
RX PubMed=11851911; DOI=10.1046/j.1365-313x.2001.01185.x;
RA Signora L., De Smet I., Foyer C.H., Zhang H.;
RT "ABA plays a central role in mediating the regulatory effects of nitrate on
RT root branching in Arabidopsis.";
RL Plant J. 28:655-662(2001).
RN [16]
RP FUNCTION.
RX PubMed=11172073; DOI=10.1073/pnas.98.4.2047;
RA Oswald O., Martin T., Dominy P.J., Graham I.A.;
RT "Plastid redox state and sugars: interactive regulators of nuclear-encoded
RT photosynthetic gene expression.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:2047-2052(2001).
RN [17]
RP FUNCTION.
RX PubMed=11996676; DOI=10.1186/1471-2229-2-4;
RA To J.P.C., Reiter W.-D., Gibson S.I.;
RT "Mobilization of seed storage lipid by Arabidopsis seedlings is retarded in
RT the presence of exogenous sugars.";
RL BMC Plant Biol. 2:4-4(2002).
RN [18]
RP FUNCTION.
RX PubMed=12136027; DOI=10.1093/genetics/161.3.1247;
RA Nambara E., Suzuki M., Abrams S., McCarty D.R., Kamiya Y., McCourt P.;
RT "A screen for genes that function in abscisic acid signaling in Arabidopsis
RT thaliana.";
RL Genetics 161:1247-1255(2002).
RN [19]
RP FUNCTION.
RX PubMed=12529517; DOI=10.1104/pp.011916;
RA Brocard-Gifford I.M., Lynch T.J., Finkelstein R.R.;
RT "Regulatory networks in seeds integrating developmental, abscisic acid,
RT sugar, and light signaling.";
RL Plant Physiol. 131:78-92(2003).
RN [20]
RP FUNCTION, AND INDUCTION BY IMBIBITION AND GLUCOSE.
RX PubMed=12857824; DOI=10.1104/pp.103.020347;
RA Price J., Li T.-C., Kang S.G., Na J.K., Jang J.-C.;
RT "Mechanisms of glucose signaling during germination of Arabidopsis.";
RL Plant Physiol. 132:1424-1438(2003).
RN [21]
RP INDUCTION, DEVELOPMENTAL STAGE, AND TISSUE SPECIFICITY.
RX PubMed=12970489; DOI=10.1104/pp.103.021089;
RA Arroyo A., Bossi F., Finkelstein R.R., Leon P.;
RT "Three genes that affect sugar sensing (abscisic acid insensitive 4,
RT abscisic acid insensitive 5, and constitutive triple response 1) are
RT differentially regulated by glucose in Arabidopsis.";
RL Plant Physiol. 133:231-242(2003).
RN [22]
RP FUNCTION.
RX PubMed=15118859; DOI=10.1007/s00425-004-1279-5;
RA Pourtau N., Mares M., Purdy S., Quentin N., Rueel A., Wingler A.;
RT "Interactions of abscisic acid and sugar signalling in the regulation of
RT leaf senescence.";
RL Planta 219:765-772(2004).
RN [23]
RP FUNCTION.
RX PubMed=15053765; DOI=10.1111/j.1365-313x.2004.02028.x;
RA Ton J., Mauch-Mani B.;
RT "Beta-amino-butyric acid-induced resistance against necrotrophic pathogens
RT is based on ABA-dependent priming for callose.";
RL Plant J. 38:119-130(2004).
RN [24]
RP FUNCTION.
RX PubMed=15502012; DOI=10.1104/pp.104.049650;
RA Guimaraes R.L., Stotz H.U.;
RT "Oxalate production by Sclerotinia sclerotiorum deregulates guard cells
RT during infection.";
RL Plant Physiol. 136:3703-3711(2004).
RN [25]
RP FUNCTION.
RX PubMed=16098105; DOI=10.1111/j.1365-313x.2005.02468.x;
RA Acevedo-Hernandez G.J., Leon P., Herrera-Estrella L.R.;
RT "Sugar and ABA responsiveness of a minimal RBCS light-responsive unit is
RT mediated by direct binding of ABI4.";
RL Plant J. 43:506-519(2005).
RN [26]
RP FUNCTION.
RX PubMed=16113213; DOI=10.1104/pp.105.065698;
RA Jakab G., Ton J., Flors V., Zimmerli L., Metraux J.-P., Mauch-Mani B.;
RT "Enhancing Arabidopsis salt and drought stress tolerance by chemical
RT priming for its abscisic acid responses.";
RL Plant Physiol. 139:267-274(2005).
RN [27]
RP FUNCTION.
RX PubMed=16339784; DOI=10.1093/jxb/erj026;
RA Verslues P.E., Bray E.A.;
RT "Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci
RT in low water potential-induced ABA and proline accumulation.";
RL J. Exp. Bot. 57:201-212(2006).
RN [28]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=16844907; DOI=10.1105/tpc.106.041277;
RA Penfield S., Li Y., Gilday A.D., Graham S., Graham I.A.;
RT "Arabidopsis ABA INSENSITIVE4 regulates lipid mobilization in the embryo
RT and reveals repression of seed germination by the endosperm.";
RL Plant Cell 18:1887-1899(2006).
RN [29]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [30]
RP INTERACTION WITH SPK1; SCAR2 AND SCAR3.
RX PubMed=17267444; DOI=10.1242/dev.02792;
RA Uhrig J.F., Mutondo M., Zimmermann I., Deeks M.J., Machesky L.M.,
RA Thomas P., Uhrig S., Rambke C., Hussey P.J., Huelskamp M.;
RT "The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell
RT morphogenesis.";
RL Development 134:967-977(2007).
RN [31]
RP FUNCTION, AND INDUCTION BY TREHALOSE.
RX PubMed=17031512; DOI=10.1007/s11103-006-9082-2;
RA Ramon M., Rolland F., Thevelein J.M., van Dijck P., Leyman B.;
RT "ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and
RT starch breakdown.";
RL Plant Mol. Biol. 63:195-206(2007).
RN [32]
RP INTERACTION WITH MED18, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=24451981; DOI=10.1038/ncomms4064;
RA Lai Z., Schluttenhofer C.M., Bhide K., Shreve J., Thimmapuram J., Lee S.Y.,
RA Yun D.-J., Mengiste T.;
RT "MED18 interaction with distinct transcription factors regulates multiple
RT plant functions.";
RL Nat. Commun. 5:3064-3064(2014).
CC -!- FUNCTION: Transcription regulator that probably binds to the GCC-box
CC pathogenesis-related promoter element. Binds also to the S-box (5'-
CC CACTTCCA-3') photosynthesis-associated nuclear genes-related (PhANGs-
CC related) promoter element, and thus acts as a transcription inhibitor.
CC Involved in the regulation of gene expression by stress factors and by
CC components of stress signal transduction pathways. May have a function
CC in the deetiolation process. Confers sensitivity to abscisic acid
CC (ABA), and regulates the ABA signaling pathway during seed germination,
CC upon nitrate-mediated lateral root inhibition, in hexokinase-dependent
CC sugar responses (including feed-back regulation of photosynthesis and
CC mobilization of storage lipid during germination), and in response to
CC osmotic stress mediated by NaCl, KCl or mannitol. Plays a role in
CC sucrose sensing or signaling, especially at low fluence far red light.
CC Also involved in plant response to glucose treatment, especially at low
CC concentration and in young seedlings. Required for the trehalose-
CC mediated root inhibition and starch accumulation in cotyledons,
CC probably by inhibiting starch breakdown. However, seems to not be
CC involved in sugar-mediated senescence. Required for the ABA-dependent
CC beta-amino-butyric acid (BABA) signaling pathway. BABA primes ABA
CC synthesis and promotes resistance to drought and salt, and leads to a
CC prime callose accumulation that confers resistance against necrotrophic
CC pathogens such as A.brassicicola and P.cucumerina. Seems to be involved
CC in resistance to S.sclerotiorum probably by regulating the ABA-mediated
CC stomatal closure apparently by antagonistic interaction with oxalate.
CC Negative regulator of low water potential-induced Pro accumulation
CC whose effect is decreased by high levels of sugar.
CC {ECO:0000269|PubMed:10629000, ECO:0000269|PubMed:10950871,
CC ECO:0000269|PubMed:10972884, ECO:0000269|PubMed:10972885,
CC ECO:0000269|PubMed:11115891, ECO:0000269|PubMed:11172073,
CC ECO:0000269|PubMed:11439129, ECO:0000269|PubMed:11851911,
CC ECO:0000269|PubMed:11996676, ECO:0000269|PubMed:12136027,
CC ECO:0000269|PubMed:12529517, ECO:0000269|PubMed:12857824,
CC ECO:0000269|PubMed:15053765, ECO:0000269|PubMed:15118859,
CC ECO:0000269|PubMed:15502012, ECO:0000269|PubMed:16098105,
CC ECO:0000269|PubMed:16113213, ECO:0000269|PubMed:16339784,
CC ECO:0000269|PubMed:16844907, ECO:0000269|PubMed:17031512,
CC ECO:0000269|PubMed:9144963, ECO:0000269|PubMed:9418043,
CC ECO:0000269|PubMed:9634591}.
CC -!- SUBUNIT: Interacts with SPK1, SCAR2 and SCAR3 (PubMed:17267444). Binds
CC to MED18 to regulate abscisic acid responses; recruits MED18 to ABI5
CC promoter in the presence of abscisic acid (ABA) (PubMed:24451981).
CC {ECO:0000269|PubMed:17267444, ECO:0000269|PubMed:24451981}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:24451981}.
CC -!- TISSUE SPECIFICITY: In seeds, mostly in embryo, and seedlings,
CC especially in vascular tissues. Confined to the hypocotyl, cotyledons,
CC the root cap, and the root quiescent center.
CC {ECO:0000269|PubMed:11115891, ECO:0000269|PubMed:12970489,
CC ECO:0000269|PubMed:16844907, ECO:0000269|PubMed:9634591}.
CC -!- DEVELOPMENTAL STAGE: Levels increase in embryos from globular stage
CC onward during seed maturation. In seedlings, levels in cotyledons and
CC hypocotyls decrease progressively to disappear 3 days after
CC germination, except after glucose treatment that makes levels constant.
CC {ECO:0000269|PubMed:11115891, ECO:0000269|PubMed:12970489}.
CC -!- INDUCTION: Only in young seedlings by ABA, imbibition, glucose, 2-
CC deoxy-glucose (2DG), trehalose, and osmotic stress.
CC {ECO:0000269|PubMed:12857824, ECO:0000269|PubMed:12970489,
CC ECO:0000269|PubMed:17031512}.
CC -!- MISCELLANEOUS: 'Salobreno' means 'salty land' in Spanish. Plants
CC lacking ABI4 are salt tolerant.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28529.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF040959; AAC39489.1; -; Genomic_DNA.
DR EMBL; AF085279; AAD25937.1; -; Genomic_DNA.
DR EMBL; AY560890; AAT44957.1; -; mRNA.
DR EMBL; CP002685; AEC09798.1; -; Genomic_DNA.
DR EMBL; DQ446612; ABE65896.1; -; mRNA.
DR EMBL; DQ653050; ABK28529.1; ALT_SEQ; mRNA.
DR PIR; G84826; G84826.
DR RefSeq; NP_181551.1; NM_129580.2.
DR AlphaFoldDB; A0MES8; -.
DR SMR; A0MES8; -.
DR BioGRID; 3952; 10.
DR STRING; 3702.AT2G40220.1; -.
DR PaxDb; A0MES8; -.
DR PRIDE; A0MES8; -.
DR EnsemblPlants; AT2G40220.1; AT2G40220.1; AT2G40220.
DR GeneID; 818614; -.
DR Gramene; AT2G40220.1; AT2G40220.1; AT2G40220.
DR KEGG; ath:AT2G40220; -.
DR Araport; AT2G40220; -.
DR TAIR; locus:2005490; AT2G40220.
DR eggNOG; ENOG502QT85; Eukaryota.
DR HOGENOM; CLU_055535_0_0_1; -.
DR InParanoid; A0MES8; -.
DR OMA; STSFHHE; -.
DR OrthoDB; 1357338at2759; -.
DR PhylomeDB; A0MES8; -.
DR PRO; PR:A0MES8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; A0MES8; baseline and differential.
DR Genevisible; A0MES8; AT.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IPI:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IDA:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IMP:TAIR.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0048527; P:lateral root development; IMP:TAIR.
DR GO; GO:0031930; P:mitochondria-nucleus signaling pathway; IDA:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:2000082; P:regulation of L-ascorbic acid biosynthetic process; IDA:TAIR.
DR GO; GO:0032880; P:regulation of protein localization; IDA:TAIR.
DR GO; GO:0010119; P:regulation of stomatal movement; IGI:TAIR.
DR GO; GO:0010896; P:regulation of triglyceride catabolic process; IMP:TAIR.
DR GO; GO:0009749; P:response to glucose; IMP:TAIR.
DR GO; GO:0006970; P:response to osmotic stress; IMP:TAIR.
DR GO; GO:0009744; P:response to sucrose; IEP:TAIR.
DR GO; GO:0010353; P:response to trehalose; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR GO; GO:0010449; P:root meristem growth; IMP:TAIR.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR GO; GO:0005983; P:starch catabolic process; NAS:TAIR.
DR GO; GO:0010182; P:sugar mediated signaling pathway; TAS:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW Abscisic acid signaling pathway; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Plant defense; Reference proteome; Repressor; Stress response;
KW Transcription; Transcription regulation.
FT CHAIN 1..328
FT /note="Ethylene-responsive transcription factor ABI4"
FT /id="PRO_0000297916"
FT DNA_BIND 54..111
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 41..48
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 10..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 69
FT /note="E->K: In abi4-104/sis5-4; impaired ABA signaling
FT pathway in response to sucrose."
FT /evidence="ECO:0000269|PubMed:10972885,
FT ECO:0000269|PubMed:11439129"
FT CONFLICT 3
FT /note="P -> L (in Ref. 3; AAT44957)"
FT /evidence="ECO:0000305"
FT CONFLICT 193
FT /note="Missing (in Ref. 3; AAT44957)"
FT /evidence="ECO:0000305"
FT CONFLICT 230
FT /note="T -> A (in Ref. 3; AAT44957)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 328 AA; 35671 MW; B6B710475E34D08F CRC64;
MDPLASQHQH NHLEDNNQTL THNNPQSDST TDSSTSSAQR KRKGKGGPDN SKFRYRGVRQ
RSWGKWVAEI REPRKRTRKW LGTFATAEDA ARAYDRAAVY LYGSRAQLNL TPSSPSSVSS
SSSSVSAASS PSTSSSSTQT LRPLLPRPAA ATVGGGANFG PYGIPFNNNI FLNGGTSMLC
PSYGFFPQQQ QQQNQMVQMG QFQHQQYQNL HSNTNNNKIS DIELTDVPVT NSTSFHHEVA
LGQEQGGSGC NNNSSMEDLN SLAGSVGSSL SITHPPPLVD PVCSMGLDPG YMVGDGSSTI
WPFGGEEEYS HNWGSIWDFI DPILGEFY
