ID   STU1_CHAGB              Reviewed;        1111 AA.
AC   Q2H0S9;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Protein STU1;
GN   Name=STU1; ORFNames=CHGG_04617;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: Microtubule binding protein that promotes the stabilization
CC       of dynamic microtubules. Required for mitotic spindle formation (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with microtubules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus
CC       {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CLASP family. {ECO:0000305}.
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DR   EMBL; CH408032; EAQ87998.1; -; Genomic_DNA.
DR   RefSeq; XP_001223831.1; XM_001223830.1.
DR   AlphaFoldDB; Q2H0S9; -.
DR   STRING; 38033.XP_001223831.1; -.
DR   PRIDE; Q2H0S9; -.
DR   EnsemblFungi; EAQ87998; EAQ87998; CHGG_04617.
DR   GeneID; 4391605; -.
DR   eggNOG; ENOG502QT5T; Eukaryota.
DR   HOGENOM; CLU_004060_0_0_1; -.
DR   InParanoid; Q2H0S9; -.
DR   OMA; TMSTNGC; -.
DR   OrthoDB; 149571at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   Pfam; PF12348; CLASP_N; 2.
DR   SMART; SM01349; TOG; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Microtubule; Mitosis;
KW   Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..1111
FT                   /note="Protein STU1"
FT                   /id="PRO_0000272285"
FT   REPEAT          95..133
FT                   /note="HEAT 1"
FT   REPEAT          167..205
FT                   /note="HEAT 2"
FT   REGION          225..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          476..751
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..554
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        599..635
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..723
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1111 AA;  120187 MW;  8B64DA273C63553C CRC64;
     MSEILTDDQV ANLIALLRAD VSIDTKVQQV TVVKSSIKQH MVPESCIVPV FEALHLASSS
     QHALLVNAGF TALNHLFTRL VRQDPRSLTK EGTRALPLIV EKLGDQKEKF RQLASQALAT
     LYKVAPVEVE RSVRNIAMVG KNARAKEASL HWLLQMHQEQ GLQFRAYVPT MMELLEDADG
     MVRDVAKSTV IELFRNAPGP AKSDLKKQLK NFKVRPAIEQ AIVKELNPTS SAPASQPDPE
     SVEPSYVNTT RELDEIFREM HGYFEGKETE QNWLKREESV TKLRRLIAGN AATDFHDQFL
     TGLRALLDGI IKAVVSLRTS LSKEGCSLIQ EIAKAYGPAM DPMVEILMQT FIKLTAATKK
     IASAQANTTV DTIISKVTYN NRIMQHVWLA CQDKNVQPRL YASGWLRTLL AKEAHHKNHV
     EHTGGLDLIE KCIKKGLSDA NPGVREKMRA TYWMFAGVWP AKAEAIMNGL DSTAARLLQN
     DPNNPKSPKK PEGGARPGLG LSKSTMGTSK PSVREAMMAQ KRAMTTKTVP TRPGSAMSHF
     SPAKSVSSLS QPPPAAPTVR ARPESAMLGS TGGISGAPMR PGRRKVETAR PATAGPYSVR
     SHDQPSAEQT SPPSRPKPKA VTPKSITSSP KRTAPKMARS ATVSGEPQLP TPTRAGSPKV
     MGSPRATPSR SVPPTVAPPS SSPSKRHEDF SLVVPIMTSS ASPPREEQRF VKPVEDEDMD
     MSPSDTPSKP GQHSPDAPAS PPQTVAAVDE EPISITTPLR SVEVAVPSPP SASRSLEVYE
     DPLTREQLTT PKLIFGPVLE DRSVNEDAAI LQQAVRQQQE QQQQQQQQNG AANGMALSPE
     KLKQNQRLLD SGISKVQQRS LDVHGFRKLQ GIIRDSDTKP TTGTALLTDD KFDALVAGLF
     DFLESPLTNL APEKTQDVKA QVLATIKLLL KRTRASFQPH VSRGLESLLR ARAVYEGRTH
     IVSGLELLAA DLAGLGDASE IVLVLCRMLS DLDVDSAAHA AAGGVGGGAG RSLSMGLHVL
     REMLDARGAA FVPSDAELAA LAALAGGCLE SLESAVRMDA VLLCVALHAR VGDARFWEAL
     KGVKEDPKSL ITYYIVKRQR EVGAAGVGQA A