STU1_GIBZE
ID STU1_GIBZE Reviewed; 1145 AA.
AC Q4I9B7; A0A098DXA6; A0A0E0SJ77; V6RCY4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Protein STU1;
GN Name=STU1; ORFNames=FGRRES_06191, FGSG_06191;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: Microtubule binding protein that promotes the stabilization
CC of dynamic microtubules. Required for mitotic spindle formation (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with microtubules. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus
CC {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CLASP family. {ECO:0000305}.
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DR EMBL; DS231665; ESU12256.1; -; Genomic_DNA.
DR EMBL; HG970334; CEF86490.1; -; Genomic_DNA.
DR RefSeq; XP_011324832.1; XM_011326530.1.
DR AlphaFoldDB; Q4I9B7; -.
DR STRING; 5518.FGSG_06191P0; -.
DR PRIDE; Q4I9B7; -.
DR EnsemblFungi; ESU12256; ESU12256; FGSG_06191.
DR GeneID; 23553329; -.
DR KEGG; fgr:FGSG_06191; -.
DR VEuPathDB; FungiDB:FGRAMPH1_01G19717; -.
DR eggNOG; ENOG502QT5T; Eukaryota.
DR HOGENOM; CLU_004060_0_0_1; -.
DR InParanoid; Q4I9B7; -.
DR Proteomes; UP000070720; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR Pfam; PF12348; CLASP_N; 2.
DR SMART; SM01349; TOG; 3.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Microtubule; Mitosis;
KW Nucleus; Reference proteome; Repeat.
FT CHAIN 1..1145
FT /note="Protein STU1"
FT /id="PRO_0000272290"
FT REPEAT 96..134
FT /note="HEAT 1"
FT REPEAT 168..206
FT /note="HEAT 2"
FT REGION 226..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..655
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..788
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1145 AA; 124928 MW; BDD638BEDA434AE9 CRC64;
MADTKLTDQQ VADLNTILRS DSPLDAKVQY VTIIKSGIKQ HNVPESSVAQ LFEGLRAATT
SQHAALVNAG FTALNHLLTR LSRQDPKLLS KEAARTLPLV VDKLGDQKDK FRSLASHSLV
TLFSVAPADV EKYVRNTAMV GKNPRAKETS MHWLLQMHNE NGLPFRTYVP VLMELLEDAD
GMVRDAAKNT VIELFRSAPN AAKSDLKRQL KTFKVRPAIE QAIVKELIPT SSRPETPAAP
AEPTPEPAPR KTFSASTSSA AERPITPGID TKPEVLEPLY VNTNRELDDM IKEMAWFFEG
KETEHNWLKR ENSVHKLRRL IAGNVTDFSD TFLAGVKSIL DGIIKVITSL RTSLCKEGCG
LIQEIAYTFG PAMDPLIEQL MQCFVKLSAG TKKISSQLAN VTVNTILSQV TYTPRLMQHI
WFACQDKNVA PRTYATEWLK TILKKEGHHK HHLEHTGGVD IVEKCLKKGL ADANPAVREK
TRSTFWVFWG IWPAKADAIM ADLDGTAQKL LNKDPSNPNS AKAAESVARP GLGLSKSTMG
TSKPSSIREA MMAQRKANAA KNLPARPGSA MAQLSPEKIT TTTSSASSKS SGARSRPETG
GMSGAPMRPS RKRPEMAARP ATAGPYSVRD MDPGSPESVR SKTPKPRETT PKRTVPRTRP
GHASHASESS LASPSSVRTG QKSAASPRAS PTKLKQSQST MLSMSSPSRA DEDFTMLVPS
MANFRTSQRP APPPQRAASV PPEAPEELST LVTEIAPQNI PQAAAEPTSQ PTLEPELEPQ
PEPEATPTPV VDPVAEAVDQ TMDETVKPEE PVHIIPEPVI EPTPEPSASM QADQAPAASA
PTLQVYEDPF TDEQTNSKPT FNLPVLEDKP VNADTASLPS VHAQSPVTQN IEAPDRAKQS
LRLLESGIKR IKAKTLDVHG FRKLQSLLRD SKGIFADDKF EALLIGLFQY LEDPLSGTSP
EKAQDIKAQI LATIRLLLKK ERDNFQPHVS RGLESLLETR SAYDIRAHIV SGVEVLADEL
VTIGDGSEIV VVLTRRLQNV DSSTTEGSRI LSTGMHVLRT MLDKRPNFMP TGTELGQLAA
LAGRCLASAD SGVRMDAVQL CVALHSRVGE QTFWDALKDV QDDPKSLITY YIVKRQREQA
PTIAA
