ID   STX19_PONAB             Reviewed;         294 AA.
AC   Q5RAL4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Syntaxin-19;
GN   Name=STX19;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in endosomal trafficking of the epidermal growth
CC       factor receptor (EGFR). {ECO:0000250|UniProtKB:Q8R1Q0}.
CC   -!- SUBUNIT: Interacts with EGFR. {ECO:0000250|UniProtKB:Q8R1Q0}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8R1Q0};
CC       Peripheral membrane protein {ECO:0000250|UniProtKB:Q8R1Q0}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q8R1Q0}.
CC   -!- SIMILARITY: Belongs to the syntaxin family. {ECO:0000305}.
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DR   EMBL; CR859001; CAH91196.1; -; mRNA.
DR   RefSeq; NP_001125702.1; NM_001132230.1.
DR   RefSeq; XP_009236943.1; XM_009238668.1.
DR   AlphaFoldDB; Q5RAL4; -.
DR   SMR; Q5RAL4; -.
DR   STRING; 9601.ENSPPYP00000015239; -.
DR   GeneID; 100172626; -.
DR   KEGG; pon:100172626; -.
DR   CTD; 415117; -.
DR   eggNOG; KOG0810; Eukaryota.
DR   HOGENOM; CLU_042423_2_0_1; -.
DR   InParanoid; Q5RAL4; -.
DR   OMA; MLQQGKW; -.
DR   TreeFam; TF313763; -.
DR   Proteomes; UP000001595; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd00179; SynN; 1.
DR   InterPro; IPR010989; SNARE.
DR   InterPro; IPR015708; STX19.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR006011; Syntaxin_N.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; PTHR19957; 1.
DR   PANTHER; PTHR19957:SF29; PTHR19957:SF29; 1.
DR   Pfam; PF00804; Syntaxin; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   SUPFAM; SSF47661; SSF47661; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Coiled coil; Cytoplasm; Membrane; Reference proteome;
KW   Transport.
FT   CHAIN           1..294
FT                   /note="Syntaxin-19"
FT                   /id="PRO_0000263711"
FT   DOMAIN          209..271
FT                   /note="t-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
SQ   SEQUENCE   294 AA;  34243 MW;  10C443F38B4E3275 CRC64;
     MKDRLQELKQ RTKEIELSRD SHVSTTETEE QGVFLQQAVI YEREPVAERH LHEIQKLQES
     INNLADNVQK FGQQQKSLVA SMRRFSLLKR ESTVTKEVKI QAEYINRSLN DLVKEVKKSE
     VENGPSSVVT RILKSQHAAM FCHFQQIMFI YNDTIAAKQE KCKTFILRQL EVAGKEMSEE
     DVNDMLHQGK WEVFNESLLT EINITKAQLS EIEQRHKELV NLENQIKDLR DLFIQLSLLV
     EEQGESINNI EMTVNSTKEY VNNTKEKFGL AVKYKKRNPC RVLCCWCCPC CSSK