ID   STX6_CAEEL              Reviewed;         122 AA.
AC   P83528;
DT   19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Putative syntaxin 6;
GN   Name=syx-6; ORFNames=C15C7.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Potentially involved in docking of synaptic vesicles at
CC       presynaptic active zones. {ECO:0000250|UniProtKB:Q08850}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type IV
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the syntaxin family. {ECO:0000305}.
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DR   EMBL; FO080550; CCD64586.1; -; Genomic_DNA.
DR   RefSeq; NP_508544.2; NM_076143.5.
DR   AlphaFoldDB; P83528; -.
DR   SMR; P83528; -.
DR   STRING; 6239.C15C7.1; -.
DR   EPD; P83528; -.
DR   PaxDb; P83528; -.
DR   PeptideAtlas; P83528; -.
DR   EnsemblMetazoa; C15C7.1.1; C15C7.1.1; WBGene00015789.
DR   UCSC; C15C7.1; c. elegans.
DR   WormBase; C15C7.1; CE30865; WBGene00015789; syx-6.
DR   eggNOG; KOG3202; Eukaryota.
DR   GeneTree; ENSGT00940000170320; -.
DR   HOGENOM; CLU_061883_2_1_1; -.
DR   InParanoid; P83528; -.
DR   OMA; NDDKRQW; -.
DR   OrthoDB; 1563292at2759; -.
DR   PhylomeDB; P83528; -.
DR   PRO; PR:P83528; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00015789; Expressed in embryo and 3 other tissues.
DR   GO; GO:0000138; C:Golgi trans cisterna; IDA:WormBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:GOC.
DR   GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016081; P:synaptic vesicle docking; ISS:UniProtKB.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; PTHR19957; 1.
DR   Pfam; PF05739; SNARE; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Neurotransmitter transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..122
FT                   /note="Putative syntaxin 6"
FT                   /id="PRO_0000210243"
FT   TOPO_DOM        1..100
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          31..93
FT                   /note="t-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
SQ   SEQUENCE   122 AA;  14035 MW;  7CDEABB18C6823B1 CRC64;
     MSNYRYSKLN EEEISLEDMP SSANQILTRQ EQIIQEQDDE LELVGNSVRT LRGMSSMIGD
     ELDQQSTMLD DLGQEMEYSE TRLDTAMKKM AKLTHLEDES SQCKMIMVLS ALLFFLVFVL
     LV