ID   STX8B_DICDI             Reviewed;         250 AA.
AC   Q54IX6;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable syntaxin-8B;
GN   Name=syn8B; ORFNames=DDB_G0288439;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the syntaxin family. {ECO:0000305}.
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DR   EMBL; AAFI02000111; EAL63245.1; -; Genomic_DNA.
DR   RefSeq; XP_636754.1; XM_631662.1.
DR   AlphaFoldDB; Q54IX6; -.
DR   SMR; Q54IX6; -.
DR   STRING; 44689.DDB0231545; -.
DR   PaxDb; Q54IX6; -.
DR   EnsemblProtists; EAL63245; EAL63245; DDB_G0288439.
DR   GeneID; 8626632; -.
DR   KEGG; ddi:DDB_G0288439; -.
DR   dictyBase; DDB_G0288439; syn8B.
DR   eggNOG; KOG3202; Eukaryota.
DR   HOGENOM; CLU_099972_0_0_1; -.
DR   InParanoid; Q54IX6; -.
DR   OMA; CGYWIVI; -.
DR   PhylomeDB; Q54IX6; -.
DR   PRO; PR:Q54IX6; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR   GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR   GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; PTHR19957; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..250
FT                   /note="Probable syntaxin-8B"
FT                   /id="PRO_0000319999"
FT   TOPO_DOM        1..213
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical; Anchor for type IV membrane protein"
FT   TOPO_DOM        235..250
FT                   /note="Vesicular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          148..210
FT                   /note="t-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT   COILED          73..100
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   250 AA;  28480 MW;  89B01C3922177EB2 CRC64;
     MGDYWLNEHD NIVKLINSLT ADIKEYSIQQ RNNPGIVQKN TPAKLRNGLV HITNEILRLQ
     DSLTYGNNRN IQEKELLRRK NKVESLISMK NQLNSTLDAA INNTSQKNEL MGNNNGVGIG
     YSNRQFGKPK ETEATKQFDN QQLFTNQQHI MREQDESLDL LSQSIMRQKN MAHAMSNELD
     QHNEMLDDVE IGTDAVSMRL RNANRRMETI KQNAGSTCMI VCIVILIILI VVLIATDSGC
     KIYNDPKHCP