ID   STXB6_BOVIN             Reviewed;         210 AA.
AC   Q2YDL1;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Syntaxin-binding protein 6;
GN   Name=STXBP6;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms non-fusogenic complexes with SNAP25 and STX1A and may
CC       thereby modulate the formation of functional SNARE complexes and
CC       exocytosis.
CC   -!- SUBUNIT: Part of a ternary complex containing SNAP25 and STX1A that can
CC       be dissociated by NAPA and NSF. Interacts with STX4A (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
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DR   EMBL; BC110173; AAI10174.1; -; mRNA.
DR   RefSeq; NP_001069506.1; NM_001076038.2.
DR   AlphaFoldDB; Q2YDL1; -.
DR   SMR; Q2YDL1; -.
DR   STRING; 9913.ENSBTAP00000028368; -.
DR   PaxDb; Q2YDL1; -.
DR   PRIDE; Q2YDL1; -.
DR   GeneID; 534718; -.
DR   KEGG; bta:534718; -.
DR   CTD; 29091; -.
DR   eggNOG; KOG1983; Eukaryota.
DR   InParanoid; Q2YDL1; -.
DR   OrthoDB; 201698at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR   GO; GO:0035542; P:regulation of SNARE complex assembly; IEA:InterPro.
DR   CDD; cd14681; PH-STXBP6; 1.
DR   CDD; cd15892; R-SNARE_STXBP6; 1.
DR   InterPro; IPR028258; Sec3-PIP2_bind.
DR   InterPro; IPR037821; STXBP6_PH.
DR   InterPro; IPR037822; STXBP6_SNARE.
DR   InterPro; IPR042855; V_SNARE_CC.
DR   Pfam; PF15277; Sec3-PIP2_bind; 1.
DR   Pfam; PF00957; Synaptobrevin; 1.
DR   SMART; SM01313; Sec3-PIP2_bind; 1.
DR   PROSITE; PS50892; V_SNARE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Coiled coil; Cytoplasm; Membrane; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NFX7"
FT   CHAIN           2..210
FT                   /note="Syntaxin-binding protein 6"
FT                   /id="PRO_0000283574"
FT   DOMAIN          151..210
FT                   /note="v-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00290"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NFX7"
SQ   SEQUENCE   210 AA;  23667 MW;  7C131A9A7E74B2DD CRC64;
     MSAKSAISKE IFAPLDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL SVTNKKPTQA
     SITKVKQFEG STSFVRRSQW MLEQLRQVKG IDPNRDSAEF DLLFENAFDQ WVASTASEKC
     TFFQILHHTC QRYLTDRKPE FINCQSKIMG GNSILHSAAD SVTSAVQKAS QALNERGERL
     GRAEEKTEDL KNSAQQFAET AHKLAMKHKC