ID   ST_BFPYV                Reviewed;         145 AA.
AC   P13895;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   29-SEP-2021, entry version 89.
DE   RecName: Full=Small t antigen;
DE            Short=ST;
DE            Short=ST-AG;
OS   Budgerigar fledgling disease virus (BFPyV) (Aves polyomavirus 1).
OC   Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC   Sepolyvirales; Polyomaviridae; Gammapolyomavirus.
OX   NCBI_TaxID=1891747;
OH   NCBI_TaxID=9224; Psittacidae (parrots).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2838972; DOI=10.1016/0042-6822(88)90660-5;
RA   Rott O., Kroeger M., Mueller H., Hobom G.;
RT   "The genome of budgerigar fledgling disease virus, an avian polyomavirus.";
RL   Virology 165:74-86(1988).
CC   -!- FUNCTION: Promotes efficient viral genome replication by accelerating
CC       both G1 and S phase progression of the cell cycle. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with host PPP2R1A; the interaction inhibits PP2A
CC       activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=Small t antigen;
CC         IsoId=P13895-1; Sequence=Displayed;
CC       Name=Large T antigen;
CC         IsoId=P13894-1; Sequence=External;
CC   -!- DOMAIN: The common region of ST and LT proteins comprises the J domain.
CC       This domain is essential for multiple viral activities, including
CC       virion assembly, viral DNA replication, transformation and
CC       transcriptional activation. This domain is also required for cyclin A-
CC       transactivating activity of ST (By similarity). {ECO:0000250}.
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DR   EMBL; M20775; AAB59761.1; -; Genomic_DNA.
DR   PIR; E29194; TVVPBD.
DR   SMR; P13895; -.
DR   PRIDE; P13895; -.
DR   Proteomes; UP000134051; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   Pfam; PF00226; DnaJ; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   3: Inferred from homology;
KW   Activator; Alternative splicing; Early protein; Host cytoplasm;
KW   Host nucleus; Host-virus interaction; Oncogene; Phosphoprotein;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..145
FT                   /note="Small t antigen"
FT                   /id="PRO_0000115051"
FT   DOMAIN          6..82
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT   REGION          58..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   145 AA;  16988 MW;  794AC88B2223046D CRC64;
     MASLRRLTEL LCLPVTATAA DIKTAYRRTA LKYHPDKGGD EEKMKELNTL MEEFRETEGL
     RADETLEDSD PEPEESGYAT FENVSVPDID GAFFKLMKLK KCMQTYFSVN ERRKQDIRPE
     YFELFKAFQD VPWKVLEDFF TSEMF