ID   ST_POVBO                Reviewed;         124 AA.
AC   P24852; Q90052;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 3.
DT   29-SEP-2021, entry version 83.
DE   RecName: Full=Small t antigen;
DE            Short=ST;
DE            Short=ST-AG;
OS   Bovine polyomavirus (BPyV) (Bos taurus polyomavirus 1).
OC   Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC   Sepolyvirales; Polyomaviridae; Epsilonpolyomavirus.
OX   NCBI_TaxID=1891754;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2167926; DOI=10.1099/0022-1317-71-8-1723;
RA   Schuurman R., Sol C., van der Noordaa J.;
RT   "The complete nucleotide sequence of bovine polyomavirus.";
RL   J. Gen. Virol. 71:1723-1735(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND ALTERNATIVE SPLICING.
RX   PubMed=1279101; DOI=10.1099/0022-1317-73-11-2879;
RA   Schuurman R., Jacobs M., van Strien A., van der Noordaa J., Sol C.;
RT   "Analysis of splice sites in the early region of bovine polyomavirus:
RT   evidence for a unique pattern of large T mRNA splicing.";
RL   J. Gen. Virol. 73:2879-2886(1992).
CC   -!- FUNCTION: Promotes efficient viral genome replication by accelerating
CC       both G1 and S phase progression of the cell cycle.
CC       {ECO:0000250|UniProtKB:P03081}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus
CC       {ECO:0000250|UniProtKB:P03081}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=Small t antigen;
CC         IsoId=P24852-1; Sequence=Displayed;
CC       Name=Large T antigen;
CC         IsoId=P24851-1; Sequence=External;
CC   -!- DOMAIN: The common region of ST and LT proteins comprises the J domain.
CC       This domain is essential for multiple viral activities, including
CC       virion assembly, viral DNA replication, transformation and
CC       transcriptional activation. This domain is also required for cyclin A-
CC       transactivating activity of ST. {ECO:0000250|UniProtKB:P03081}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB24091.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; D13942; BAA03041.1; -; Genomic_DNA.
DR   EMBL; S48204; AAB24091.1; ALT_SEQ; mRNA.
DR   PIR; JU0358; TVVPBJ.
DR   RefSeq; NP_040789.1; NC_001442.1. [P24852-1]
DR   SMR; P24852; -.
DR   GeneID; 29031002; -.
DR   KEGG; vg:29031002; -.
DR   Proteomes; UP000008476; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
PE   2: Evidence at transcript level;
KW   Activator; Alternative splicing; Early protein; Host cytoplasm;
KW   Host nucleus; Host-virus interaction; Oncogene; Phosphoprotein;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..124
FT                   /note="Small t antigen"
FT                   /id="PRO_0000115054"
FT   DOMAIN          10..96
FT                   /note="J"
SQ   SEQUENCE   124 AA;  14011 MW;  2C2ADE72967DF64D CRC64;
     MELTSEEYEE LRGLLGTPDI GNADTLKKAF LKACKVHHPD KGGNEEAMKR LLYLYNKAKI
     AASATTSQVW YFLIIGYISL KNKNIYLPKI FWLRFQNMAP HSGNSGGKNS IKALMSKICI
     VMRN