ID   SUBI_SYNY3              Reviewed;         352 AA.
AC   Q01903; P74545;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Sulfate-binding protein;
DE   Flags: Precursor;
GN   Name=sbpA; OrderedLocusNames=slr1452;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8425067; DOI=10.1007/bf00019958;
RA   Kohn C., Schumann J.;
RT   "Nucleotide sequence and homology comparison of two genes of the sulfate
RT   transport operon from the cyanobacterium Synechocystis sp. PCC 6803.";
RL   Plant Mol. Biol. 21:409-412(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: This protein specifically binds sulfate and is involved in
CC       its transmembrane transport.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- INDUCTION: By sulfur deprivation.
CC   -!- SIMILARITY: Belongs to the prokaryotic sulfate-binding protein family.
CC       {ECO:0000305}.
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DR   EMBL; X67911; CAA48109.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA18651.1; -; Genomic_DNA.
DR   PIR; S76739; S76739.
DR   AlphaFoldDB; Q01903; -.
DR   SMR; Q01903; -.
DR   STRING; 1148.1653740; -.
DR   PaxDb; Q01903; -.
DR   EnsemblBacteria; BAA18651; BAA18651; BAA18651.
DR   KEGG; syn:slr1452; -.
DR   eggNOG; COG1613; Bacteria.
DR   InParanoid; Q01903; -.
DR   OMA; KDFGGWK; -.
DR   PhylomeDB; Q01903; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:1901681; F:sulfur compound binding; IEA:InterPro.
DR   GO; GO:1902358; P:sulfate transmembrane transport; IEA:InterPro.
DR   CDD; cd01005; PBP2_CysP; 1.
DR   InterPro; IPR000957; Sulphate/thiosulphate-bd_CS.
DR   InterPro; IPR034408; Sulphate/thiosulphate_BS.
DR   InterPro; IPR005669; Thiosulph/SO4-bd.
DR   PANTHER; PTHR30368; PTHR30368; 1.
DR   TIGRFAMs; TIGR00971; 3a0106s03; 1.
DR   PROSITE; PS00401; PROK_SULFATE_BIND_1; 1.
DR   PROSITE; PS00757; PROK_SULFATE_BIND_2; 1.
PE   2: Evidence at transcript level;
KW   Periplasm; Reference proteome; Signal; Stress response; Sulfate transport;
KW   Transport.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000255"
FT   CHAIN           41..352
FT                   /note="Sulfate-binding protein"
FT                   /id="PRO_0000031686"
FT   CONFLICT        277
FT                   /note="R -> A (in Ref. 2; BAA18651)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   352 AA;  38128 MW;  93B2EC03EEAC21AF CRC64;
     MARSAFGWGF SVIAVLMVGS ITACNTTTTT EPGQGENASQ APANLTLVSY AVTRDAFEKI
     IPKFTEEWKS KTGQDVTFEQ SYGGSGSQTR AVVDGLEADI VALALSSDVQ KIESAGLIQP
     GWEQEAPNGS IVTNSVIAFV TKASDNIKVE KWADLANPEV KVITANPKTS GGARWNFLGI
     WGSVTKTGGT EEQAFDFAGK VLANAPVLPK DARESTDVFY KQGQGNVLLN YENEVLLAKQ
     KGENQPYIIP QDFNVSISGP VAVVDTTVDK KGTREVRDAF VQYLFTPEAQ QIFAETGFRP
     VNEEVLAKFA SQYPKVENLA TIEEFGGWKK AQAEFFDEGG IFDKVITKIG RQ