ID   ABIG1_LACLC             Reviewed;         249 AA.
AC   Q48725;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Abortive phage resistance protein AbiGi;
GN   Name=abiGI;
OS   Lactococcus lactis subsp. cremoris (Streptococcus cremoris).
OG   Plasmid pCI750.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1359;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UC653;
RX   PubMed=8795193; DOI=10.1128/aem.62.9.3075-3082.1996;
RA   O'Connor L., Coffey A., Daly C., Fitzgerald G.F.;
RT   "AbiG, a genotypically novel abortive infection mechanism encoded by
RT   plasmid pCI750 of Lactococcus lactis subsp. cremoris UC653.";
RL   Appl. Environ. Microbiol. 62:3075-3082(1996).
RN   [2]
RP   EFFECT ON PHAGES.
RC   STRAIN=UC653;
RX   PubMed=9872803; DOI=10.1128/aem.65.1.330-335.1999;
RA   O'Connor L., Tangney M., Fitzgerald G.F.;
RT   "Expression, regulation, and mode of action of the AbiG abortive infection
RT   system of Lactococcus lactis subsp. cremoris UC653.";
RL   Appl. Environ. Microbiol. 65:330-335(1999).
CC   -!- FUNCTION: Confers resistance to phages by a mechanism of abortive
CC       infection. Seems to act by interfering with phage RNA synthesis. Does
CC       not act at the level of phage DNA synthesis.
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DR   EMBL; U60336; AAB38312.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q48725; -.
DR   InterPro; IPR021223; AbiGi.
DR   Pfam; PF10899; AbiGi; 1.
PE   4: Predicted;
KW   Plasmid.
FT   CHAIN           1..249
FT                   /note="Abortive phage resistance protein AbiGi"
FT                   /id="PRO_0000064425"
SQ   SEQUENCE   249 AA;  29401 MW;  885720D28047C138 CRC64;
     MAFLPRYYPE NIEYLKISKE NTPLKEWYIP MTCFCDIPLH QMSYHAEGKA QTGYGKFSIA
     LHKKFGINNG IQPVQYLNSN SIPTEELRNA ISILLSDNGQ IYSDEALISL SNHLFEYMRR
     IKPLDGSMKK WDKEGKKYVE IKKNFHDEHE WRYIPDFESD ELPFLLYRQD DIIAESSSQF
     YTKSITETKN GLLNFSVSDI RYIFVDSILS REKLISFIKR KQKGKRIPRA EKDILISKIL
     VYDEIKEDW