ID   ABIL1_ARATH             Reviewed;         298 AA.
AC   Q8S8M5; Q8GWF6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Protein ABIL1;
DE   AltName: Full=Abl interactor-like protein 1;
DE            Short=AtABIL1;
GN   Name=ABIL1; OrderedLocusNames=At2g46225; ORFNames=T3F17;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INTERACTION WITH SCAR2.
RX   PubMed=15659634; DOI=10.1105/tpc.104.027987;
RA   Basu D., Le J., El-Din El-Assal S., Huang S., Zhang C., Mallery E.L.,
RA   Koliantz G., Staiger C.J., Szymanski D.B.;
RT   "DISTORTED3/SCAR2 is a putative Arabidopsis WAVE complex subunit that
RT   activates the Arp2/3 complex and is required for epidermal morphogenesis.";
RL   Plant Cell 17:502-524(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in regulation of actin and microtubule organization.
CC       Part of a WAVE complex that activates the Arp2/3 complex (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Binds SCAR2.
CC   -!- INTERACTION:
CC       Q8S8M5; Q5XPJ9: SCAR2; NbExp=3; IntAct=EBI-1547655, EBI-1547795;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=Q8S8M5-1; Sequence=Displayed;
CC   -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, hypocotyls,
CC       cotyledons, leaves, stems, and flowers. {ECO:0000269|PubMed:15659634}.
CC   -!- SIMILARITY: Belongs to the ABI family. {ECO:0000305}.
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DR   EMBL; AY817012; AAW49256.1; -; mRNA.
DR   EMBL; AC005397; AAM15048.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC10659.1; -; Genomic_DNA.
DR   EMBL; AK118876; BAC43461.1; -; mRNA.
DR   EMBL; AY085146; AAM61699.1; -; mRNA.
DR   RefSeq; NP_566067.1; NM_130185.3. [Q8S8M5-1]
DR   AlphaFoldDB; Q8S8M5; -.
DR   SMR; Q8S8M5; -.
DR   BioGRID; 4565; 2.
DR   IntAct; Q8S8M5; 11.
DR   STRING; 3702.AT2G46225.2; -.
DR   iPTMnet; Q8S8M5; -.
DR   PRIDE; Q8S8M5; -.
DR   ProteomicsDB; 244364; -. [Q8S8M5-1]
DR   DNASU; 819230; -.
DR   EnsemblPlants; AT2G46225.1; AT2G46225.1; AT2G46225. [Q8S8M5-1]
DR   GeneID; 819230; -.
DR   Gramene; AT2G46225.1; AT2G46225.1; AT2G46225. [Q8S8M5-1]
DR   KEGG; ath:AT2G46225; -.
DR   Araport; AT2G46225; -.
DR   eggNOG; KOG2546; Eukaryota.
DR   InParanoid; Q8S8M5; -.
DR   OMA; AAEYCEM; -.
DR   PhylomeDB; Q8S8M5; -.
DR   PRO; PR:Q8S8M5; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8S8M5; baseline and differential.
DR   Genevisible; Q8S8M5; AT.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028457; ABI.
DR   PANTHER; PTHR10460; PTHR10460; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..298
FT                   /note="Protein ABIL1"
FT                   /id="PRO_0000191794"
FT   CONFLICT        271
FT                   /note="Q -> L (in Ref. 4; BAC43461)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   298 AA;  33196 MW;  11C7CBC733886794 CRC64;
     METEISGMDN PAMTLDEVSM ERNKSFVKAL QELKNLRPQL YSAADYCEKS YLHSEQKQMV
     LDNLKDYTVK ALVNAVDHLG TVASKLTDLF DHQNSDISTM EMRASCVSQQ LLTCRTYIDK
     EGLRQQQLLA VIPLHHKHYI LPNSVNKRVH FSPLRRTDTR QNHYQAISRL QPSDAPASKS
     LSWHLGSETK STLKGTSTVA PSSKDSKAFS KTSGVFHLLG DDENIANKKP LAGSQVSGVP
     AASTAHKDLE VPKLLTAHRS LDNNPRREII QAPVRTKSVL SAFFVKQKTP KLKAGYVS