ID   SUDA_EMENI              Reviewed;        1215 AA.
AC   Q00737; C8V0X5; Q5AZB6;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 3.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Chromosome segregation protein sudA;
DE   AltName: Full=DA-box protein sudA;
GN   Name=sudA; ORFNames=AN6364;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=8849887; DOI=10.1093/genetics/142.3.777;
RA   Holt C.L., May G.S.;
RT   "An extragenic suppressor of the mitosis-defective bimD6 mutation of
RT   Aspergillus nidulans codes for a chromosome scaffold protein.";
RL   Genetics 142:777-787(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Involved in chromosome segregation in mitosis.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily. {ECO:0000305}.
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DR   EMBL; U40146; AAB42143.1; -; mRNA.
DR   EMBL; AACD01000107; EAA58748.1; -; Genomic_DNA.
DR   EMBL; BN001301; CBF69619.1; -; Genomic_DNA.
DR   PIR; S65799; S65799.
DR   RefSeq; XP_663968.1; XM_658876.1.
DR   AlphaFoldDB; Q00737; -.
DR   SMR; Q00737; -.
DR   STRING; 162425.CADANIAP00006620; -.
DR   PRIDE; Q00737; -.
DR   EnsemblFungi; CBF69619; CBF69619; ANIA_06364.
DR   EnsemblFungi; EAA58748; EAA58748; AN6364.2.
DR   GeneID; 2871258; -.
DR   KEGG; ani:AN6364.2; -.
DR   VEuPathDB; FungiDB:AN6364; -.
DR   eggNOG; KOG0964; Eukaryota.
DR   HOGENOM; CLU_001042_5_0_1; -.
DR   InParanoid; Q00737; -.
DR   OMA; DQHQSMR; -.
DR   OrthoDB; 119789at2759; -.
DR   Proteomes; UP000000560; Chromosome I.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0034990; C:nuclear mitotic cohesin complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0061775; F:cohesin loading activity; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IMP:AspGD.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:AspGD.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IBA:GO_Central.
DR   CDD; cd03272; ABC_SMC3_euk; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR041741; SMC3_ABC_euk.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF75553; SSF75553; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cell cycle; Cell division; Coiled coil; Mitosis;
KW   Nucleotide-binding; Nucleus; Reference proteome.
FT   CHAIN           1..1215
FT                   /note="Chromosome segregation protein sudA"
FT                   /id="PRO_0000119016"
FT   DOMAIN          538..650
FT                   /note="SMC hinge"
FT   REGION          313..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          177..522
FT                   /evidence="ECO:0000255"
FT   COILED          684..1091
FT                   /evidence="ECO:0000255"
FT   BINDING         32..39
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        257..259
FT                   /note="Missing (in Ref. 1; AAB42143)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        440
FT                   /note="Missing (in Ref. 1; AAB42143)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1215 AA;  139515 MW;  AE7BF3B3CBE8DE4C CRC64;
     MYVKQIIIQG FKSYKDQTVI EPFSPKHNVI VGRNGSGKSN FFAAIRFVLS DAYTHLGREE
     RQALLHEGSG SAVMSAYVEI IFDNSDERFP TGKPELVLRR TIGLKKDEYT LDRKNATKND
     VMNLLESAGF SRSNPYYIVP QGRVTALTNM KDSERLNLLK EVAGTQVYEA RRAESLKIMH
     ETNSKREKID ELLDFINERL AELEEEKDEL RNFQEKDKER RCLEYTIYSR EQQEIASFLD
     SLEEQRQTGV EDTDINRDRF IQGEKEMAQV DAEIAECKQQ IEFLKVDKAQ LEDERREASK
     ALAQVELQAK SLSDNQAAAQ ESKARHDESL KAVQSAIEER QTELKELVPR FISAKDAEDA
     ARAKLTEAET ARQRLYAKQG RNSRFKNKSE RDKWLQAEIK NNNASISSVQ SVLSQTQEDI
     NDIENDIALL EPETERLRQQ IDGRGDTIQS VEQQVQAAKD ERDRLMDQRK YVDWPRTSCA
     TLTIHRELWR EEAKLDSILI NASNEVDRAE RNLSQMMDHN TSRGIAAVRR IKRQHNLEGV
     YGTLAELFEV NDRYRTAVEV TAGQSLFHYV VDTDDTATKV LEILQHEKAG RVTFMPLNRL
     RTKPLNMPKA SDTIPMIEKL QYDRAYEKAF QHVFGKTIIC PNLQVASQYA RSHGVNATTP
     EGDRSDKRGA LTGGFHDSRQ SRLDAVKNLA KWRDEYETKK SRGSEIRKEL EELDQLITRA
     VGELQKLEQQ RHQVQNSSGP LRQELRSKRD LLQKQNDNLD AKRRALRNIE GNLAALKDQV
     DAFEAELSSP FHKALTDEEE ARLESLNSNV QEYRREYQEL SGKRSELETR KSVLEVELRE
     NLNPRLDQLL AQDADIADED GQGNIKETQR EQKRLTKVLD KLAQRLAQVD ESMEQANSRV
     TELTQRNAES RRELEELAKS IEKHQRRMEK SMQKKAALTK QAAECAANIR DLGVLPDEAF
     TKYKNTDSNT VVKKLHKVNE ALKKYAHVNK KAFEQYNNFT KQRETLTSRR EELDASQKSI
     DDLISVLDHR KDEAIERTFK QVSREFATIF EKLVPAGRGR LIIQRKTDRT QRAEDDLESE
     DEEAKHSVEN YVGVGISVSF NSKHDDQQRI QQLSGGQKSL CALALVFAIQ ACDPAPFYLF
     DEIDANLDAQ YRTAVAQMLK TISDSTNGQF ICTTFRPEML HVAEKCYGVS FRQKASTIDV
     VSREEALKFV EEQKS