ID   SUFB_SHIFL              Reviewed;         495 AA.
AC   Q83KW2;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=FeS cluster assembly protein SufB;
GN   Name=sufB; OrderedLocusNames=SF1713, S1845;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: The SufBCD complex acts synergistically with SufE to
CC       stimulate the cysteine desulfurase activity of SufS. The SufBCD complex
CC       contributes to the assembly or repair of oxygen-labile iron-sulfur
CC       clusters under oxidative stress. May facilitate iron uptake from
CC       extracellular iron chelators under iron limitation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Part of the SufBCD complex that contains SufB, SufC and SufD.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0051 (ycf24) family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN43289.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP17177.1; -; Genomic_DNA.
DR   RefSeq; NP_707582.1; NC_004337.2.
DR   AlphaFoldDB; Q83KW2; -.
DR   SMR; Q83KW2; -.
DR   STRING; 198214.SF1713; -.
DR   EnsemblBacteria; AAN43289; AAN43289; SF1713.
DR   EnsemblBacteria; AAP17177; AAP17177; S1845.
DR   GeneID; 1027795; -.
DR   KEGG; sfl:SF1713; -.
DR   KEGG; sfx:S1845; -.
DR   PATRIC; fig|198214.7.peg.2027; -.
DR   HOGENOM; CLU_026231_0_0_6; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   InterPro; IPR010231; SUF_FeS_clus_asmbl_SufB.
DR   InterPro; IPR000825; SUF_FeS_clus_asmbl_SufBD.
DR   InterPro; IPR037284; SUF_FeS_clus_asmbl_SufBD_sf.
DR   InterPro; IPR045595; SufBD_N.
DR   Pfam; PF01458; SUFBD; 1.
DR   Pfam; PF19295; SufBD_N; 1.
DR   SUPFAM; SSF101960; SSF101960; 1.
DR   TIGRFAMs; TIGR01980; sufB; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..495
FT                   /note="FeS cluster assembly protein SufB"
FT                   /id="PRO_0000147374"
FT   CONFLICT        177
FT                   /note="T -> P (in Ref. 2; AAP17177)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   495 AA;  54749 MW;  26753150CF6FC4B9 CRC64;
     MSRNTEATDD VKTWTGGPLN YKEGFFTQLA TDELAKGINE EVVRAISAKR NEPEWMLEFR
     LNAYRAWLEM EEPHWLKAHY DKLNYQDYSY YSAPSCGNCD DTCASEPGAV QQTGANAFLS
     KEVEAAFEQL GVPVREGKEV AVDAIFDSVS VATTYREKLA EQGIIFCSFG EAIHDHTELV
     RKYLGTVVPG NDNFFAALNA AVASDGTFIY VPKGVRCPME LSTYFRINAE KTGQFERTIL
     VADEDSYVSY IEGCSAPVRD SYQLHAAVVE VIIHKNAEVK YSTVQNWFPG DNNTGGILNF
     VTKRALCEGE NSKMSWTQSE TGSAITWKYP SCILRGDNSI GEFYSVALTS GHQQADTGTK
     MIHIGKNTKS TIISKGISAG HSQNSYRGLV KIMPTATNAR NFTQCDSMLI GANCGAHTFP
     YVECRNNSAQ LEHEATTSRI GEDQLFYCLQ RGISEEDAIS MIVNGFCKDV FSELPLEFAV
     EAQKLLAISL EHSVG