ID   SUFD_BACSU              Reviewed;         437 AA.
AC   O32165;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=FeS cluster assembly protein SufD;
GN   Name=sufD; Synonyms=yurX; OrderedLocusNames=BSU32700;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: The SufBCD complex acts synergistically with SufE to
CC       stimulate the cysteine desulfurase activity of SufS. The SufBCD complex
CC       contributes to the assembly or repair of oxygen-labile iron-sulfur
CC       clusters under oxidative stress. May facilitate iron uptake from
CC       extracellular iron chelators under iron limitation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Part of the SufBCD complex that contains SufB, SufC and SufD.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0051 (ycf24) family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB15259.1; -; Genomic_DNA.
DR   PIR; G70019; G70019.
DR   RefSeq; NP_391149.1; NC_000964.3.
DR   RefSeq; WP_003228602.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; O32165; -.
DR   SMR; O32165; -.
DR   IntAct; O32165; 2.
DR   MINT; O32165; -.
DR   STRING; 224308.BSU32700; -.
DR   jPOST; O32165; -.
DR   PaxDb; O32165; -.
DR   PRIDE; O32165; -.
DR   EnsemblBacteria; CAB15259; CAB15259; BSU_32700.
DR   GeneID; 938871; -.
DR   KEGG; bsu:BSU32700; -.
DR   PATRIC; fig|224308.179.peg.3541; -.
DR   eggNOG; COG0719; Bacteria.
DR   InParanoid; O32165; -.
DR   OMA; PNCESHQ; -.
DR   PhylomeDB; O32165; -.
DR   BioCyc; BSUB:BSU32700-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   InterPro; IPR000825; SUF_FeS_clus_asmbl_SufBD.
DR   InterPro; IPR037284; SUF_FeS_clus_asmbl_SufBD_sf.
DR   InterPro; IPR011542; SUF_FeS_clus_asmbl_SufD.
DR   InterPro; IPR045595; SufBD_N.
DR   Pfam; PF01458; SUFBD; 1.
DR   Pfam; PF19295; SufBD_N; 1.
DR   SUPFAM; SSF101960; SSF101960; 1.
DR   TIGRFAMs; TIGR01981; sufD; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..437
FT                   /note="FeS cluster assembly protein SufD"
FT                   /id="PRO_0000388725"
SQ   SEQUENCE   437 AA;  48293 MW;  459EAC0A36F39C6A CRC64;
     MTLGTKLSVD QEYLKSFSEK HQEPAWLKNL RLQALEQAED LPMPKPDKTK ITNWNFTNFA
     KHTVDNEPLS SLEDLTDEVK ALIDIENEDK TLYVQRDQTP AHLSLSQELK DKGVIFTDIL
     TAAREHSDLV EKYFMKDGVK VDEHKLTALH AALVNGGAFL YVPKNVQVET PVQAVYVHES
     NDTALFNHVL IVAEDHSSVT YVENYISTVN PKDAVFNIIS EVITGDNASV TYGAVDNLSS
     GVTTYVNRRG AARGRDSKIE WALGLMNDGD TISENTTNLY GDGTYGDTKT VVVGRGEQTE
     NFTTQIIHFG KASEGYILKH GVMKDSASSI FNGIGKIEHG ASKANAEQES RVLMLSEKAR
     GDANPILLID EDDVTAGHAA SVGRVDPIQL YYLMSRGIPK EEAERLVIYG FLAPVVNELP
     IEGVKKQLVS VIERKVK